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[钠钾-ATP酶失活期间细胞膜的超极化]

[Hyperpolarization of the cell membrane during Na,K-ATPase inactivation].

作者信息

Kabakov A Iu

出版信息

Biofizika. 1988 Mar-Apr;33(2):297-302.

PMID:2839243
Abstract

The relationship equation between the resting potential and potassium and sodium active currents is deduced in terms of a generally accepted model of electrogenesis. It is demonstrated that an increase of Na,K-ATPase activity to the estimated magnitude results in hyperpolarization of the cell membrane (CM), but the subsequent increase of the activity led to CM depolarisation. CM depolarisation results in an increase of the cell volume.

摘要

根据普遍接受的电发生模型推导了静息电位与钾和钠主动电流之间的关系方程。结果表明,钠钾ATP酶活性增加到估计幅度会导致细胞膜(CM)超极化,但随后活性增加会导致CM去极化。CM去极化导致细胞体积增加。

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