Rogozinski T T, Jablonska S, Jarzabek-Chorzelska M
Department of Dermatology, Warsaw Medical Academy, Poland.
Int J Dermatol. 1988 Jun;27(5):322-6. doi: 10.1111/j.1365-4362.1988.tb02362.x.
Human papillomavirus-induced plane warts most often occur in the second decade of age. Afterward, they either spontaneously regress or are eradicated in the course of various treatments. As proved by in vivo and in vitro tests as well as clinical observations, they most often affect and persist longer in immunocompromised hosts. In this work it was confirmed that specific-ie, anti-HPV-directed, cell-mediated immunologic response plays a role in spontaneous regression of plane warts and that preservation of nonspecific immunity is prerequisite for spontaneous regression of plane warts.
人乳头瘤病毒引起的扁平疣最常出现在第二个十年年龄段。此后，它们要么自然消退，要么在各种治疗过程中被根除。体内和体外试验以及临床观察证明，它们在免疫功能低下的宿主中最常受到影响且持续时间更长。在这项研究中证实，特异性即针对人乳头瘤病毒的细胞介导免疫反应在扁平疣的自然消退中起作用，并且保留非特异性免疫是扁平疣自然消退的先决条件。
