Ghadami Yazdi Elham, Minaei Mohamad Bagher, Hashem Dabaghian Fataneh, Ebrahim Zadeh Ardakani Mohamad, Ranjbar Ali Mohammad, Rastegari Mohamad, Ghadami Yazdi Ali
Research Deputy of Traditional Medicine, Tehran University of Medical Sciences, Tehran, IR Iran.
Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences Tehran, IR Iran.
Iran Red Crescent Med J. 2014 Oct 5;16(10):e16386. doi: 10.5812/ircmj.16386. eCollection 2014 Oct.
Wart is a skin disease with circular appendages, which is called "suloul" in Iranian traditional medicine (ITM). According to ITM literature, warts have different types and causes. The most important mechanism is excretion of materials (Khelt) from body to skin and mucus; its causative material is often phlegm, black bile or a combination of them. To treat warts, it is necessary to consider the patient's life style, modify his dietary intake and moisturize his temperament.
This study aimed to compare Myrtus communis L. and Descurainia sophia L. as a method of ITM, versus salicylic acid in treatment of wart.
In this study, conducted in Yazd, Iran, 100 patients were selected and randomly divided into four groups. Group 1) salicylic acid, group 2) salicylic acid and D. sophia L. group 3) M. communis L. group 4) M. communis L. and D. sophia L. Numbers, sizes of lesions and symptoms, on days 0, 20, 40 and 90 were examined and analyzed. The relapse rate was investigated three months after. Changes of sizes and numbers of warts in each period of time in each group, compared to baseline, were assessed by Wilcoxon Signed Rank test. To compare these changes between the groups, Kruskal Wallis test was used.
In this study 100 patients participated, 69% of which were female. Compared to baseline, mean ± SD of changes for the number of warts in day 40 were 1.12 ± 4.2, 0.96 ± 2.5, 1.32 ± 5.1 and 0.04 ± 0.2 respectively in the four groups (P = 0.02). Mean ± SD of changes for the number of warts in day 90 were 1.84 ± 4.5, 1.56 ± 2.8, 1.24 ± 5.1 and 0.04 ± 0.6 respectively in the four groups (P = 0.03). In addition mean ± SD of changes for the size of warts in day 40 were 0.96 ± 1.8, 1.03 ± 2.4, 2.47 ± 3.0 and 0.45 ± 1.7 respectively in the four groups (P < 0.001). Mean ± SD of changes for the size of warts in day 90 were 1.24 ± 2.1, 1.3 ± 2.3, 2.45 ± 3.1 and 0.45 ± 1.7 respectively in the four groups (P < 0.001). Relapse was not seen in any groups after three months. The frequency of side effects was similar after three months.
M. communis L. can be used as a topical treatment for warts. It not only shows more rapid response than salicylic acid, but also has fewer side effects. It seems that D. sophia L. can modify the digestion process and patients can excrete large amounts of the substance that causes warts. Therefore, it is better to use it more than 40 days. According to our investigation, in ITM, considering the cause and mechanism of disease generation and the causing materials of the disease, different treatments should be applied for each patient. Although applying an appropriate treatment is necessary, a unique treatment for all the patients cannot be available.
疣是一种带有圆形附属物的皮肤病，在伊朗传统医学（ITM）中被称为“苏卢尔”。根据ITM文献，疣有不同类型和病因。最重要的机制是物质（赫尔特）从身体排泄到皮肤和黏液；其致病物质通常是痰、黑胆汁或它们的组合。治疗疣时，有必要考虑患者的生活方式，调整其饮食摄入并调节其气质。
本研究旨在比较作为ITM方法的香桃木和播娘蒿与水杨酸治疗疣的效果。
本研究在伊朗亚兹德进行，选取100例患者并随机分为四组。第1组）水杨酸，第2组）水杨酸和播娘蒿，第3组）香桃木，第4组）香桃木和播娘蒿。在第0、20、40和90天检查并分析病变的数量、大小和症状。三个月后调查复发率。通过Wilcoxon符号秩检验评估每组在每个时间段内与基线相比疣的大小和数量变化。为比较组间这些变化，使用Kruskal Wallis检验。
本研究有100例患者参与，其中69%为女性。与基线相比，四组在第40天时疣数量变化的均值±标准差分别为1.12±4.2、0.96±2.5、1.32±5.1和0.04±0.2（P = 0.02）。四组在第90天时疣数量变化的均值±标准差分别为1.84±4.5、1.56±2.8、1.24±5.1和0.04±0.6（P = 0.03）。此外，四组在第40天时疣大小变化的均值±标准差分别为0.96±1.8、1.03±2.4、2.47±3.0和0.45±1.7（P < 0.001）。四组在第90天时疣大小变化的均值±标准差分别为1.24±2.1、1.3±2.3、2.45±3.1和0.45±1.7（P < 0.001）。三个月后任何组均未出现复发。三个月后侧效应的发生率相似。
香桃木可作为疣的局部治疗药物。它不仅比水杨酸显示出更快的反应，而且副作用更少。播娘蒿似乎可以调节消化过程，患者可以排出大量导致疣的物质。因此，最好使用超过40天。根据我们的调查，在ITM中，考虑疾病产生的原因和机制以及疾病的致病物质，应为每位患者应用不同的治疗方法。虽然应用适当的治疗是必要的，但不可能有适用于所有患者的单一治疗方法。
