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慢性肉芽肿病的临床特征与当前治疗方法

Clinical features and current management of chronic granulomatous disease.

作者信息

Forrest C B, Forehand J R, Axtell R A, Roberts R L, Johnston R B

机构信息

Children's Hospital of Pennsylvania, Philadelphia.

出版信息

Hematol Oncol Clin North Am. 1988 Jun;2(2):253-66.

PMID:2839458
Abstract

Chronic granulomatous disease (CGD) is a diverse disorder characterized by several clinical presentations and a multitude of metabolic defects. The authors summarize the clinical features and current management of CGD, offer a definition of the disease based on molecular defects of the respiratory burst, and present their experience with trimethoprim/sulfamethoxazole prophylaxis.

摘要

慢性肉芽肿病(CGD)是一种具有多种临床表现和众多代谢缺陷的复杂疾病。作者总结了CGD的临床特征和当前治疗方法,基于呼吸爆发的分子缺陷对该疾病进行了定义,并介绍了他们使用甲氧苄啶/磺胺甲恶唑预防治疗的经验。

相似文献

1
Clinical features and current management of chronic granulomatous disease.慢性肉芽肿病的临床特征与当前治疗方法
Hematol Oncol Clin North Am. 1988 Jun;2(2):253-66.
2
Cellular and molecular effects of recombinant interferon gamma in chronic granulomatous disease.重组干扰素γ在慢性肉芽肿病中的细胞和分子效应
Hematol Oncol Clin North Am. 1988 Jun;2(2):267-76.
3
The respiratory burst oxidase.呼吸爆发氧化酶。
Hematol Oncol Clin North Am. 1988 Jun;2(2):201-12.
4
Antibacterial prophylaxis in chronic granulomatous disease. A case report.
Isr J Med Sci. 1983 Nov;19(11):1004-5.
5
Classification of chronic granulomatous disease.慢性肉芽肿病的分类。
Hematol Oncol Clin North Am. 1988 Jun;2(2):241-52.
6
Delineation of the phagocyte NADPH oxidase through studies of chronic granulomatous diseases of childhood.通过对儿童慢性肉芽肿病的研究来描绘吞噬细胞NADPH氧化酶。
Int J Tissue React. 1993;15(3):99-103.
7
Trimethoprim-sulphamethoxazole.甲氧苄啶-磺胺甲恶唑
Indian Pediatr. 1987 Nov;24(11):1035-7.
8
Chronic granulomatous disease: a syndrome of phagocyte oxidase deficiencies.慢性肉芽肿病:一种吞噬细胞氧化酶缺乏综合征。
Medicine (Baltimore). 1983 Sep;62(5):286-309.
9
Chronic granulomatous disease.慢性肉芽肿病
Annu Rev Med. 1992;43:117-24. doi: 10.1146/annurev.me.43.020192.001001.
10
Modern management of chronic granulomatous disease.慢性肉芽肿病的现代管理
Br J Haematol. 2008 Feb;140(3):255-66. doi: 10.1111/j.1365-2141.2007.06880.x.

引用本文的文献

1
Hepatic abscess in patients with chronic granulomatous disease.慢性肉芽肿病患者的肝脓肿
Ann Surg. 2002 Mar;235(3):383-91. doi: 10.1097/00000658-200203000-00010.
2
Neutrophil disorders and their management.中性粒细胞疾病及其管理。
J Clin Pathol. 2001 Jan;54(1):7-19. doi: 10.1136/jcp.54.1.7.
3
Chronic granulomatous disease and other disorders of neutrophil function.慢性肉芽肿病及其他中性粒细胞功能障碍。
Clin Rev Allergy Immunol. 2000 Oct;19(2):141-56. doi: 10.1385/CRIAI:19:2:141.
4
X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase.X连锁慢性肉芽肿病:编码呼吸爆发氧化酶gp91-phox组分的CYBB基因突变。
Am J Hum Genet. 1998 Jun;62(6):1320-31. doi: 10.1086/301874.
5
The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase.胞质亚基p67phox含有一个NADPH结合位点,该位点参与白细胞NADPH氧化酶的催化作用。
J Clin Invest. 1996 Aug 15;98(4):977-83. doi: 10.1172/JCI118882.
6
A novel polymorphism in the coding region of CYBB, the human gp91-phox gene.人gp91-噬中性粒细胞氧化酶基因(CYBB)编码区的一种新型多态性。
Hum Genet. 1996 May;97(5):611-3. doi: 10.1007/BF02281870.
7
Resolution of hepatic abscess after interferon gamma in chronic granulomatous disease.慢性肉芽肿病中γ干扰素治疗后肝脓肿的消退
Arch Dis Child. 1993 Oct;69(4):443-5. doi: 10.1136/adc.69.4.443.
8
Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558.X连锁慢性肉芽肿病中细胞色素b558表达降低,其gp91-噬氧细胞氧化酶基因启动子区域发生突变。
J Clin Invest. 1994 Sep;94(3):1205-11. doi: 10.1172/JCI117437.
9
The p47phox mouse knock-out model of chronic granulomatous disease.慢性肉芽肿病的p47phox小鼠基因敲除模型。
J Exp Med. 1995 Sep 1;182(3):751-8. doi: 10.1084/jem.182.3.751.
10
Recombinant human interferon-gamma in patients with chronic granulomatous disease--European follow up study.重组人干扰素γ用于慢性肉芽肿病患者——欧洲随访研究
Eur J Pediatr. 1995 Apr;154(4):295-8. doi: 10.1007/BF01957365.