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意大利工作场所甲醛暴露的国家估计。

National Estimates of Exposure to Formaldehyde in Italian Workplaces.

机构信息

Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority (INAIL), Viale Stefano Gradi, 55, 00143 Rome, Italy.

出版信息

Ann Work Expo Health. 2017 Jan 1;61(1):33-43. doi: 10.1093/annweh/wxw004.

Abstract

PURPOSE

Formaldehyde is classified as human carcinogen and the association with nasopharyngeal cancer has been observed in many epidemiological studies. The aim of this study is to evaluate data about occupational exposure levels to formaldehyde in the Italian working force.

METHODS

Airborne concentrations of formaldehyde were extracted from the Italian database on occupational exposure to carcinogens and refer to the period 1996-2014. Descriptive statistics were calculated for exposure-related variables. The number of workers potentially exposed was estimated for the activity sectors better characterized in the database. An analysis through linear mixed models was performed to determine factors influencing the exposure level.

RESULTS

A total of 1610 formaldehyde exposure measurements were selected from the database, having an overall arithmetic mean of 0.12 mg m-3 and a geometric mean of 0.04 mg m-3. The activity sectors with the highest number of measurements were the manufacturing of chemicals and chemicals products (N = 529) in men and the health and social work in women (N = 105). The number of workers potentially exposed in the selected sectors was 49450, and the most predictive independent variables of the exposure level resulted to be the occupational group and the year of measurement.

CONCLUSIONS

The occupational exposure to formaldehyde occurs in a variety of different sectors, but currently workers at higher risk are those employed in the healthcare sector and in the wood processing industry. Prevention measures have to be targeted to reduce the risk to workers' health, also in a gender perspective. This study confirms the important role of occupational exposure databases as a valuable source of data for the epidemiological assessment of risks in workplaces.

摘要

目的

甲醛被归类为人类致癌物,许多流行病学研究都观察到了它与鼻咽癌之间的关联。本研究旨在评估意大利劳动力中职业暴露于甲醛的数据。

方法

从意大利职业暴露于致癌物数据库中提取了甲醛的空气浓度数据,该数据涵盖了 1996 年至 2014 年期间的数据。对暴露相关变量进行了描述性统计分析。对数据库中特征描述较好的活动部门的潜在暴露工人数量进行了估计。通过线性混合模型分析确定了影响暴露水平的因素。

结果

从数据库中选择了 1610 次甲醛暴露测量值,总体算术平均值为 0.12mg/m³,几何平均值为 0.04mg/m³。测量值数量最多的活动部门是男性的化学品和化学制品制造(N=529)和女性的卫生和社会工作(N=105)。在所选择的部门中,潜在暴露的工人数量为 49450 人,暴露水平的最具预测性的独立变量是职业群体和测量年份。

结论

职业暴露于甲醛发生在许多不同的部门,但目前处于较高风险的工人是从事医疗保健部门和木材加工业的工人。预防措施必须针对减少工人健康风险,同时也要考虑到性别视角。本研究证实了职业暴露数据库作为评估工作场所风险的流行病学评估的重要数据源的重要作用。

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