Dugheri Stefano, Bonari Alessandro, Pompilio Ilenia, Colpo Marco, Mucci Nicola, Arcangeli Giulio
Laboratorio di Igiene e Tossicologia Industriale, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Dipartimento di Medicina Sperimentale e Clinica, Università Degli Studi di Firenze, Florence, Italy.
Saf Health Work. 2018 Dec;9(4):479-485. doi: 10.1016/j.shaw.2018.05.002. Epub 2018 May 31.
The aim of this study is to validate an integrated air monitoring approach for assessing airborne formaldehyde (FA) in the workplace. An active sampling by silica gel impregnated with 2,4-dinitrophenylhydrazine, a passive solid phase microextraction technique using O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine as on-fiber derivatization reagent, an electrochemical direct-reading monitor, and an enzyme-based badge were evaluated and tested over a range of 0.020-5.12 ppm, using dynamically generated FA air concentrations. Simple linear regression analysis showed the four methods were suitable for evaluating airborne FA. Personal and area samplings in 12 anatomy pathology departments showed that the international occupational exposure limits in the GESTIS database were frequently exceeded. This monitoring approach would allow a fast, easy-to-use, and economical evaluation of both current work practices and eventual changes made to reduce FA vapor concentrations.
本研究的目的是验证一种用于评估工作场所空气中甲醛（FA）的综合空气监测方法。对用2,4-二硝基苯肼浸渍的硅胶进行主动采样、使用O-(2,3,4,5,6-五氟苄基)羟胺作为纤维上衍生试剂的被动固相微萃取技术、电化学直读监测仪和酶基徽章在0.020 - 5.12 ppm范围内进行了评估和测试，使用动态生成的FA空气浓度。简单线性回归分析表明这四种方法适用于评估空气中的FA。在12个解剖病理科室进行的个人和区域采样显示，GESTIS数据库中的国际职业接触限值经常被超过。这种监测方法将允许对当前的工作实践以及为降低FA蒸汽浓度而进行的最终变更进行快速、易用且经济的评估。
