Bansal Rhea A, Tadros Susan, Bansal Amolak S
Immunology Department, St Helier Hospital, Wrythe Lane, Carshalton, Surrey SM5 1AA, UK.
St Helier Hospital, Wrythe Lane, Carshalton, Surrey SM5 1AA, UK.
Case Reports Immunol. 2017;2017:7958924. doi: 10.1155/2017/7958924. Epub 2017 Mar 15.
. Allergy to beer is often due to specific proteins in barley and sometimes to lipid transfer protein. Allergy to wine is frequently due to a sensitivity to grape proteins. We present a rare case of allergy to beer, wine, and cider resulting from IgE reactivity to yeasts and moulds which also explained the patient's additional sensitivity to yeast extracts and blue cheese. . The patient's symptoms included throat and facial itching accompanied by mild wheeze and severe urticaria. Diagnosis of allergy to yeast was confirmed by specific IgE testing as well as that to relevant foods and beverages. The patient's ongoing management included advice to avoid beer, wine, and other food groups containing specific yeasts, in addition to carrying a short acting nonsedating antihistamine as well as an adrenaline autoinjector. . Cases of yeast allergy are extremely rare in medical literature but may be underrecognised and should be considered in patients presenting with reactions to alcoholic beverages and other yeast-containing products.
对啤酒过敏通常是由于大麦中的特定蛋白质,有时也由于脂质转移蛋白。对葡萄酒过敏常常是由于对葡萄蛋白敏感。我们报告一例罕见的对啤酒、葡萄酒和苹果酒过敏的病例,其原因是对酵母和霉菌的IgE反应性,这也解释了患者对酵母提取物和蓝纹奶酪的额外敏感性。患者的症状包括喉咙和面部瘙痒,伴有轻度喘息和严重荨麻疹。通过特异性IgE检测以及对相关食物和饮料的检测,确诊了对酵母的过敏。患者的持续管理包括建议避免饮用啤酒、葡萄酒以及其他含有特定酵母的食物类别,此外还要随身携带短效非镇静性抗组胺药以及肾上腺素自动注射器。在医学文献中,酵母过敏的病例极其罕见,但可能未被充分认识,对于出现对酒精饮料和其他含酵母产品反应的患者应予以考虑。