Kim Ha Yeon, Lee Kyung Hee, Kim Yeo Ju, Lee Ha Young, Kim Ga Ram, Jeon Yong Sun, Kim Jung Soo, Kim Young Sam, Kim Jun Ho
Department of Radiology, Inha University Hospital, Inha University School of Medicine, Inhang-ro 27, Jung-gu, Incheon, Republic of Korea.
Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Inhang-ro 27, Jung-gu, Incheon, Republic of Korea.
Biomed Res Int. 2017;2017:8740635. doi: 10.1155/2017/8740635. Epub 2017 Mar 15.
. To determine the association between the progression of upper lung fibrosis and paratracheal air cysts (PACs) size. . The thoracic CT images of 4573 patients were reviewed for the prevalence, size, and location of PACs and their communication with trachea. In addition, the presence of upper lung fibrosis, emphysema, and bronchiectasis was evaluated in patients with PACs and compared with a control group without PACs. Upper lung fibrosis was analyzed using a fibrosis score system. . The prevalence of PACs was 6.8%. Communication with tracheal lumen was demonstrated by 31.5% of patients with PACs. The prevalence of fibrosis, emphysema, and bronchiectasis in patients with PACs were 67.5%, 21.9%, and 28.3%, respectively. The prevalence of fibrosis was significantly different in the two groups by univariable and multivariable analysis (odds ratio = 2.077, < 0.001). 140 patients with fibrosis among PAC group underwent a previous or follow-up CT; the prevalence with increase in PAC sizes was higher in patients with increase in fibrosis score than those without it (66.2% versus 17.3%, < 0.001). . PACs appear to be highly related to upper lung fibrosis and moderately related to bronchiectasis. In patients with fibrosis, PAC sizes tended to increase with the progression of upper lung fibrosis.
. 确定上肺纤维化进展与气管旁气囊肿（PACs）大小之间的关联。. 回顾了4573例患者的胸部CT图像，以了解PACs的患病率、大小、位置及其与气管的连通情况。此外，对有PACs的患者评估了上肺纤维化、肺气肿和支气管扩张的存在情况，并与无PACs的对照组进行比较。使用纤维化评分系统分析上肺纤维化。. PACs的患病率为6.8%。31.5%有PACs的患者显示与气管腔连通。有PACs的患者中纤维化、肺气肿和支气管扩张的患病率分别为67.5%、21.9%和28.3%。单变量和多变量分析显示两组纤维化患病率有显著差异（比值比=2.077，<0.001）。PAC组中有140例纤维化患者接受了之前或后续的CT检查；纤维化评分增加的患者中PACs大小增加的患病率高于未增加的患者（66.2%对17.3%，<0.001）。. PACs似乎与上肺纤维化高度相关，与支气管扩张中度相关。在纤维化患者中，PACs大小往往随着上肺纤维化的进展而增加。
