Carulli Christian, Rizzo Anna Rosa, Innocenti Massimo
Orthopaedic Clinic, University of Florence, Florence 50139, Italy.
J Clin Med. 2017 Apr 8;6(4):44. doi: 10.3390/jcm6040044.
Hip arthropathy in haemophilic patients is disabling for hip and other common target joints. Even if bleedings in the hip are not frequent, femoroacetabular alterations may affect the functional ability of patients at a very young age. A haematologic prophylaxis combined with an adequate lifestyle and regular and low-traumatic physical activity are the keys to preventing such arthropathy. In the early stages of arthropathy, anti-inflammatory drugs and physical therapy may be sufficient to limit its progression. In cases of recurrent symptoms, viscosupplementation with hyaluronic acid, and chemical synoviorthesis are useful options. In more advanced stages, hip arthroscopy may be treated by synovectomy or loose body removal. For late stages, total hip arthroplasty (THA) is mandatory. Until a few decades ago, the clinical outcomes after hip arthroplasty were variable, due to the different management of patients and the use of old generation implants and couplings. In the last decade, the introduction of the multidisciplinary management and the use of modern cementless implants with high performing materials and less invasive surgical techniques have dramatically improved the functional results. Nowadays, as is the case for other target joints, the purpose of the management in haemophilia centers is the early detection of any hip alterations-by clinical and ultrasound (US) evaluations of patients in childhood-to reveal any early articular damage and to provide adequate treatment in case of symptoms. The present paper represents an updated review of the several approaches to hip arthropathy in haemophilia.
血友病患者的髋关节病会导致髋关节及其他常见靶关节功能丧失。即使髋关节出血不频繁,股骨髋臼改变也可能在患者幼年时影响其功能。血液学预防措施、适当的生活方式以及规律且低创伤的体育活动是预防此类关节病的关键。在关节病早期,抗炎药物和物理治疗可能足以限制其进展。对于症状反复的情况,透明质酸关节腔注射和化学性滑膜切除是有效的选择。在更晚期阶段,髋关节镜检查可通过滑膜切除术或取出游离体进行治疗。对于晚期病例,全髋关节置换术(THA)是必要的。直到几十年前,由于患者管理方式不同以及使用老式植入物和连接件,髋关节置换术后的临床结果各不相同。在过去十年中,多学科管理的引入以及使用具有高性能材料的现代非骨水泥植入物和侵入性较小的手术技术,显著改善了功能结果。如今,与其他靶关节情况一样,血友病中心管理的目的是通过对儿童患者进行临床和超声(US)评估,早期发现任何髋关节改变,以揭示任何早期关节损伤,并在出现症状时提供适当治疗。本文是对血友病髋关节病几种治疗方法的最新综述。