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抑郁症及药物治疗与小儿麻痹后遗症患者跌倒发生率的关系

Relationship of depression and medications on incidence of falls among people with late effects of polio.

作者信息

Da Silva Carolyn P, Zuckerman Bianca, Olkin Rhoda

机构信息

a School of Physical Therapy , Texas Woman's University , Houston , TX , USA.

b RehabCare , Park Manor Skilled Nursing Facility , Humble , TX , USA.

出版信息

Physiother Theory Pract. 2017 May;33(5):370-375. doi: 10.1080/09593985.2017.1307889. Epub 2017 Apr 11.

DOI:10.1080/09593985.2017.1307889
PMID:28398102
Abstract

The purpose of this study was to determine if falls in polio survivors, with or without post-polio syndrome (PPS), are related to number of medications taken, use of anti-depressant or psychoactive medications, or self-report of depression. A survey was sent to 300 members of a regional polio support group, asking them to document their fall history, medications used, and the presence of depression. Depression was measured by self-report and with the Geriatric Depression Scale, short form (GDS-15). One hundred and seventy-two usable surveys were returned with 146 of those completing the medication list. Sixty-two percent reported at least one fall in the past year. The multiple logistic regression was significant (p = 0.023), and it indicated depression to be a significant predictor (p = 0.012) of falls in polio survivors with and without PPS. The number of total medications or anti-depressant or psychoactive medications used was not related to fall incidence. Routine screening and treatment for depression may be one aspect of fall prevention which can be implemented through primary care.

摘要

本研究的目的是确定患有或未患有小儿麻痹后遗症(PPS)的小儿麻痹症幸存者的跌倒是否与所服用药物的数量、抗抑郁药或精神活性药物的使用,或抑郁症的自我报告有关。向一个地区性小儿麻痹症支持小组的300名成员发送了一份调查问卷,要求他们记录自己的跌倒史、所使用的药物以及是否患有抑郁症。通过自我报告和老年抑郁量表简表(GDS-15)来测量抑郁症。共收回172份可用的调查问卷,其中146份完成了药物清单。62%的人报告在过去一年中至少跌倒过一次。多元逻辑回归具有显著性(p = 0.023),表明抑郁症是患有或未患有PPS的小儿麻痹症幸存者跌倒的一个显著预测因素(p = 0.012)。所使用的药物总数、抗抑郁药或精神活性药物的数量与跌倒发生率无关。对抑郁症进行常规筛查和治疗可能是跌倒预防的一个方面,可通过初级保健来实施。

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