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复发性卵巢癌:放射治疗的作用

Recurrent Ovarian Cancer: The Role of Radiation Therapy.

作者信息

De Felice Francesca, Marchetti Claudia, Di Mino Andrea, Palaia Innocenza, Benevento Ilaria, Musella Angela, Musio Daniela, Tombolini Vincenzo

机构信息

*Department of Radiotherapy, Policlinico Umberto I, and †Department of Gynecological and Obstetrical Sciences and Urological Sciences, Sapienza University of Rome, Rome, Italy.

出版信息

Int J Gynecol Cancer. 2017 May;27(4):690-695. doi: 10.1097/IGC.0000000000000958.

Abstract

OBJECTIVE

The aim of this review was to present the current radiation therapy status in recurrent ovarian cancer (OC) and explore potential solution to improve clinical outcomes in this setting of patients.

MATERIALS AND METHODS

PubMed search was performed. An attempt was made to include all relevant studies. Pertinent references cited in selected articles were also considered.

RESULTS

The role of radiation therapy in recurrent OC needs to be defined. This is the largest reported analysis of published data.

CONCLUSIONS

Chemotherapy is the mainstay of recurrent OC treatment but prognosis remains very poor, and novel therapies are required to be integrated into this consolidated treatment regimen. Radiation therapy represents a valid alternative approach, even if no clear guidelines are available concerning it.

摘要

目的

本综述的目的是介绍复发性卵巢癌(OC)的当前放射治疗状况,并探索改善该类患者临床结局的潜在解决方案。

材料与方法

进行了PubMed检索。试图纳入所有相关研究。还考虑了所选文章中引用的相关参考文献。

结果

放射治疗在复发性OC中的作用需要明确。这是已发表数据中报道的最大规模分析。

结论

化疗是复发性OC治疗的主要手段,但预后仍然很差,需要将新疗法纳入这一综合治疗方案。放射治疗是一种有效的替代方法,即使尚无关于它的明确指南。

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