Antibacterial Action of Jineol Isolated from against Selected Foodborne Pathogens.

This study was undertaken to assess the antibacterial potential of 3,8-dihydroxyquinoline (jineol) isolated from against selected foodborne pathogens O157:H7 and KCTC-1621. Jineol at the tested concentration (50 μL; corresponding to 250 μg/disk) exhibited significant antibacterial effects as a diameter of inhibition zones (11.6-13.6 mm), along with minimum inhibitory concentration (MIC) and minimum bactericidal concentration values found in the range of (62.5-125 μg/mL) and (125-250 μg/mL), respectively. Jineol also exhibited significant antibacterial effects as confirmed by the reduction in bacterial cell viabilities, increasing release of potassium (K) ions (650 and 700 mmole/L) and 260 nm materials (optical density: 2.98-3.12) against both the tested pathogens, O157:H7 and KCTC-1621, respectively. Moreover, changes in the cell wall morphology of O157:H7 and KCTC-1621 cells treated with jineol at MIC further confirmed its inhibitory potential against the tested pathogens, suggesting its role as an effective antimicrobial to control foodborne pathogens.