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低剂量酵母水解物治疗肥胖与减肥

Low Dose Yeast Hydrolysate in Treatment of Obesity and Weight Loss.

作者信息

Jung Eun Young, Lee Jong Woo, Hong Yang Hee, Chang Un Jae, Suh Hyung Joo

机构信息

Department of Home Economic Education, Jeonju University, Jeonbuk 55069, Korea.

Department of Health Management, Jeonju University, Jeonbuk 55069, Korea.

出版信息

Prev Nutr Food Sci. 2017 Mar;22(1):45-49. doi: 10.3746/pnf.2017.22.1.45. Epub 2017 Mar 31.

DOI:10.3746/pnf.2017.22.1.45
PMID:28401087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5383141/
Abstract

The anti-obesity effects of yeast hydrolysate (YH) supplementation (1.0 g/d) have already been demonstrated. We investigated whether a low dose of YH (0.5 g/d, YH-500) also has the anti-obesity effects. Thirty obese women were randomly assigned to the control or YH-500 groups. After 8 weeks, weight and body mass index were significantly reduced by the YH treatment (0.5 g/d) (<0.05). The YH-500 group lost a significant amount of body fat after the 8-week treatment: fat mass 25.9 kg (baseline) versus 23.8 kg (8th week), <0.01; fat mass ratio 38.8% (baseline) versus 36.5% (8th week), <0.05. The YH-500 group showed a significant reduction in calorie intake during the 8-week treatment (<0.001). The control group wanted to eat much more food (<0.05) and sometimes thought about eating more often compared with the YH-500 group (<0.05). Whereas the control group showed a slightly increased sweet preference, the YH-500 group showed a significant reduction in sweet preference (<0.05). In conclusion, low dose YH supplementation (0.5 g/d) may induce a reductions in weight and body fat in obese women via the reduction of calorie intake.

摘要

补充酵母水解物(YH,1.0克/天)的抗肥胖作用已得到证实。我们研究了低剂量YH(0.5克/天,YH - 500)是否也具有抗肥胖作用。30名肥胖女性被随机分为对照组或YH - 500组。8周后,YH治疗组(0.5克/天)的体重和体重指数显著降低(<0.05)。YH - 500组在8周治疗后体脂显著减少:脂肪量从25.9千克(基线)降至23.8千克(第8周),<0.01;脂肪量比例从38.8%(基线)降至36.5%(第8周),<0.05。YH - 500组在8周治疗期间卡路里摄入量显著减少(<0.001)。与YH - 500组相比,对照组想吃更多的食物(<0.05),并且有时更频繁地想吃东西(<0.05)。对照组的甜味偏好略有增加,而YH - 500组的甜味偏好显著降低(<0.05)。总之,低剂量补充YH(0.5克/天)可能通过减少卡路里摄入量来降低肥胖女性的体重和体脂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db3d/5383141/d2dc6a0c9fcc/pnfs-22-045f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db3d/5383141/01cf75cb4e7c/pnfs-22-045f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db3d/5383141/d2dc6a0c9fcc/pnfs-22-045f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db3d/5383141/01cf75cb4e7c/pnfs-22-045f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db3d/5383141/d2dc6a0c9fcc/pnfs-22-045f2.jpg

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The improvement of sweet taste sensitivity with decrease in serum leptin levels during weight loss in obese females.
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