Peng Jingying, Docherty Jamie H, Dominey Andrew P, Thomas Stephen P
EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK.
GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, Hertfordshire, UK.
Chem Commun (Camb). 2017 Apr 25;53(34):4726-4729. doi: 10.1039/c7cc01085k.
A bipyridiyl-oxazoline cobalt catalyst BPOCoCl has been developed for the Markovnikov selective hydroboration of alkenes using pinacolborane and NaOBu as the in situ activator with up to >98 : 2 branched : linear selectivity (24 examples, 45-92% isolated yield).
已开发出一种联吡啶基-恶唑啉钴催化剂BPOCoCl，用于以频哪醇硼烷和叔丁醇钠作为原位活化剂，对烯烃进行马氏选择性硼氢化反应，支链与直链选择性高达>98:2（24个实例，分离产率45 - 92%）。
