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脑电图——早产儿脑损伤的重要生物标志物

EEG - A Valuable Biomarker of Brain Injury in Preterm Infants.

作者信息

Pavlidis Elena, Lloyd Rhodri O, Boylan Geraldine B

机构信息

Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), and Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.

出版信息

Dev Neurosci. 2017;39(1-4):23-35. doi: 10.1159/000456659. Epub 2017 Apr 13.

DOI:10.1159/000456659
PMID:28402972
Abstract

This review focuses on the role of electroencephalography (EEG) in monitoring abnormalities of preterm brain function. EEG features of the most common developmental brain injuries in preterm infants, including intraventricular haemorrhage, periventricular leukomalacia, and perinatal asphyxia, are described. We outline the most common EEG biomarkers associated with these injuries, namely seizures, positive rolandic sharp waves, EEG suppression/increased interburst intervals, mechanical delta brush activity, and other deformed EEG waveforms, asymmetries, and asynchronies. The increasing survival rate of preterm infants, in particular those that are very and extremely preterm, has led to a growing demand for a specific and shared characterization of the patterns related to adverse outcome in this unique population. This review includes abundant high-quality images of the EEG patterns seen in premature infants and will provide a valuable resource for everyone working in developmental neuroscience.

摘要

本综述聚焦于脑电图(EEG)在监测早产脑功能异常中的作用。描述了早产儿最常见的发育性脑损伤的脑电图特征,包括脑室内出血、脑室周围白质软化和围产期窒息。我们概述了与这些损伤相关的最常见的脑电图生物标志物,即癫痫发作、中央区正相尖波、脑电图抑制/爆发间期延长、机械性δ刷活动以及其他异常的脑电图波形、不对称性和不同步性。早产儿,尤其是极早早产儿和超早早产儿存活率的不断提高,导致对这一独特人群中与不良结局相关模式进行特定且共享特征描述的需求日益增加。本综述包含大量早产儿脑电图模式的高质量图像,将为从事发育神经科学工作的每一个人提供宝贵资源。

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1
EEG - A Valuable Biomarker of Brain Injury in Preterm Infants.脑电图——早产儿脑损伤的重要生物标志物
Dev Neurosci. 2017;39(1-4):23-35. doi: 10.1159/000456659. Epub 2017 Apr 13.
2
Electroencephalography and brain damage in preterm infants.早产儿的脑电图与脑损伤
Early Hum Dev. 2005 Mar;81(3):255-61. doi: 10.1016/j.earlhumdev.2005.01.006.
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Positive rolandic sharp waves in preterm infants with periventricular leukomalacia: their relation to background electroencephalographic abnormalities.早产儿脑室周围白质软化症中的中央区正锐波:它们与背景脑电图异常的关系。
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[Perinatal brain injury in infants with depressed EEG activities immediately after birth].出生后即刻脑电图活动抑制的婴儿围产期脑损伤
No To Hattatsu. 1996 Jan;28(1):48-52.
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Timing of periventricular leukomalacia using neonatal electroencephalography.利用新生儿脑电图确定脑室周围白质软化症的发病时间
Int J Gynaecol Obstet. 1996 Nov;55(2):111-5. doi: 10.1016/s0020-7292(96)02741-5.
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Differences between periventricular hemorrhagic infarction and periventricular leukomalacia.脑室周围出血性梗死与脑室周围白质软化症之间的差异。
Brain Dev. 2014 Aug;36(7):555-62. doi: 10.1016/j.braindev.2013.07.014. Epub 2013 Aug 23.
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A review of important electroencephalogram features for the assessment of brain maturation in premature infants.早产儿脑成熟评估的重要脑电图特征综述。
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Positive temporal sharp waves in electroencephalograms of the premature newborn.早产儿脑电图中的阳性颞部尖波。
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Rhythmic EEG patterns in extremely preterm infants: Classification and association with brain injury and outcome.极早产儿的脑电图节律模式:分类及其与脑损伤和预后的关联
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