一种来自绵参的新型环阿尔廷烷三萜糖苷。
A new cycloartane triterpenoid glycoside from Souliea vaginata.
作者信息
Wu Hai-Feng, Liu Xin, Zhu Yin-Di, Zhou Jing, Gong Ying-Ying, Ma Guo-Xu, Xu Xu-Dong, Liu Yi-Lin, Luo Zheng-Hong, Chen Di-Zhao, Zou Qiong-Yu, Zhao Zi-Jian
机构信息
b Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , PR China.
c Beijing Entry-Exit Inspection and Quarantine Bureau , Beijing , PR China.
出版信息
Nat Prod Res. 2017 Nov;31(21):2484-2490. doi: 10.1080/14786419.2017.1314283. Epub 2017 Apr 13.
One new cycloartane triterpenoid glycoside, soulieoside Q (1), together with four known compounds (2-5) were isolated from the ethanolic extract of the rhizomes of Souliea vaginata Maxim. The structure of the new compound was determined by extensive spectroscopic analysis including 1D and 2D NMR and HRESIMS, as well as chemical methods. Compound 1 was evaluated for its cytotoxic activities against HepG2 and A549 cancer cell lines.
从绵参（Souliea vaginata Maxim.）根茎的乙醇提取物中分离得到一个新的环阿尔廷烷型三萜糖苷，即绵参苷Q（1），以及四个已知化合物（2 - 5）。通过广泛的光谱分析，包括一维和二维核磁共振以及高分辨电喷雾电离质谱，还有化学方法确定了新化合物的结构。对化合物1针对肝癌细胞系HepG2和肺癌细胞系A549的细胞毒活性进行了评估。
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