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薯蓣皂素 U,一种来自. 的新型环阿屯烷三萜糖苷。

Soulieoside U, a new cycloartane triterpene glycoside from .

机构信息

Key Laboratory of Research and Utilization of Ethnomedicinal Plant Resources of Hunan Province and Key Laboratory of Hunan Higher Education for Western Hunan Medicinal Plant and Ethnobotany, Huaihua University, Huaihua 418008, China.

Beijing Key Laboratory of New Drug Discovery based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.

出版信息

Nat Prod Res. 2022 Jan;36(2):560-565. doi: 10.1080/14786419.2020.1789985. Epub 2020 Jul 9.

Abstract

One new cycloartane triterpene bisdesmoside, soulieoside U, was isolated from the rhizomes of . Its structure was elucidated by extensive analysis of the NMR and MS data. Soulieoside U was evaluated for cytotoxic activities against three human cancer cell lines.

摘要

从百合科菝葜属植物土茯苓的根茎中分离得到一个新的环阿尔廷三萜双糖苷化合物,命名为土茯苓苷 U。通过对其 NMR 和 MS 数据的综合解析,确定了该化合物的结构。对土茯苓苷 U 进行了体外抗肿瘤活性测试,结果显示该化合物对三种人癌细胞株均具有一定的细胞毒活性。

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