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创伤护理服务区域化的有效性:一项系统综述。

Effectiveness of regionalization of trauma care services: a systematic review.

作者信息

Vali Y, Rashidian A, Jalili M, Omidvari A H, Jeddian A

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Public Health. 2017 May;146:92-107. doi: 10.1016/j.puhe.2016.12.006. Epub 2017 Feb 11.

Abstract

OBJECTIVES

Improving trauma systems in various forms has always been an important aspect of health policy. While several papers have reported the implementation of a structured trauma system of care, research evidence on the effectiveness of such regionalization for improvement in trauma outcome is limited.

STUDY DESIGN

Systematic review.

METHOD

Medline, EMbase, EconLit and Health Management Information Consortium were searched, using sensitive search terms, for interventional studies that reported a trauma regionalization system as their intervention, and compared important outcomes such as mortality and preventable deaths. At least two authors assessed eligibility for inclusion and risk of bias, and extracted data from the included studies. As meta-analysis was not possible for all studies, two controlled before-after studies were included in the meta-analysis, and a narrative analysis was conducted for the other studies.

RESULTS

After title and abstract sifting, 66 papers were retrieved. After reading the full texts, a total of 24 studies from the USA, UK, Canada, Australia, and the Netherlands were included in this review. In spite of variation in study specifications, most were before-after studies with a high risk of bias. Although a reduction in mortality was shown in most studies, only two studies were eligible for meta-analysis, and the results showed a significant reduction in mortality after implementation of an organized trauma system (odds ratio 0.840, 95% confidence interval 0.756-0.924; P = 0.00).

CONCLUSION

Correlation was found between a regionalized network of trauma care and a reduction in trauma-related mortality, based on studies that did not exclude the effects of other concurrent changes on observed reductions. It is recommended that more studies with robust research designs should be conducted in a more diverse range of countries to assess the effectiveness of regionalization. Despite this limitation, the present findings support the regionalization of trauma care services.

摘要

目的

以各种形式改善创伤系统一直是卫生政策的一个重要方面。虽然有几篇论文报道了结构化创伤护理系统的实施情况,但关于这种区域化对改善创伤结局有效性的研究证据有限。

研究设计

系统评价。

方法

使用敏感检索词对医学文献数据库(Medline)、荷兰医学文摘数据库(EMbase)、经济文献数据库(EconLit)和卫生管理信息联盟数据库进行检索,以查找将创伤区域化系统作为干预措施并比较死亡率和可预防死亡等重要结局的干预性研究。至少两名作者评估纳入资格和偏倚风险,并从纳入研究中提取数据。由于并非所有研究都能进行荟萃分析,因此将两项前后对照研究纳入荟萃分析,并对其他研究进行叙述性分析。

结果

经过标题和摘要筛选,检索到66篇论文。阅读全文后,本综述共纳入了来自美国、英国、加拿大、澳大利亚和荷兰的24项研究。尽管研究规格存在差异,但大多数是前后对照研究,偏倚风险较高。尽管大多数研究显示死亡率有所降低,但只有两项研究符合荟萃分析的条件,结果显示实施有组织的创伤系统后死亡率显著降低(优势比0.840,95%置信区间0.756 - 0.924;P = 0.00)。

结论

基于未排除其他同时发生的变化对观察到的降低效果影响的研究,发现创伤护理区域化网络与创伤相关死亡率的降低之间存在关联。建议在更多样化的国家开展更多具有稳健研究设计的研究,以评估区域化的有效性。尽管存在这一局限性,但目前的研究结果支持创伤护理服务的区域化。

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