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本文引用的文献

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Granulomatous amebic encephalitis following hematopoietic stem cell transplantation.造血干细胞移植后肉芽肿性阿米巴脑炎
Surg Neurol Int. 2015 Oct 7;6(Suppl 18):S459-62. doi: 10.4103/2152-7806.166788. eCollection 2015.
2
Naegleria fowleri: pathogenesis, diagnosis, and treatment options.福氏耐格里阿米巴：发病机制、诊断及治疗选择。
Antimicrob Agents Chemother. 2015 Nov;59(11):6677-81. doi: 10.1128/AAC.01293-15. Epub 2015 Aug 10.
3
Pathogenesis of brain edema and investigation into anti-edema drugs.脑水肿的发病机制及抗水肿药物的研究
Int J Mol Sci. 2015 Apr 30;16(5):9949-75. doi: 10.3390/ijms16059949.
4
Successful treatment of an adolescent with Naegleria fowleri primary amebic meningoencephalitis.成功治疗一名患有福氏耐格里阿米巴原发性阿米巴脑膜脑炎的青少年。
Pediatrics. 2015 Mar;135(3):e744-8. doi: 10.1542/peds.2014-2292. Epub 2015 Feb 9.
5
Encephalitis caused by pathogens transmitted through organ transplants, United States, 2002-2013.2002 - 2013年美国因器官移植传播病原体导致的脑炎
Emerg Infect Dis. 2014 Sep;20(9):1443-51. doi: 10.3201/eid2009.131332.
6
Primary amoebic meningoencephalitis caused by Naegleria fowleri: an old enemy presenting new challenges.福氏耐格里阿米巴引起的原发性阿米巴脑膜脑炎：一个带来新挑战的老对手。
PLoS Negl Trop Dis. 2014 Aug 14;8(8):e3017. doi: 10.1371/journal.pntd.0003017. eCollection 2014 Aug.
7
What do we know by now about the genus Naegleria?到目前为止，我们对福氏耐格里属有哪些了解？
Exp Parasitol. 2014 Nov;145 Suppl:S2-9. doi: 10.1016/j.exppara.2014.07.011. Epub 2014 Aug 6.
8
Risk for transmission of Naegleria fowleri from solid organ transplantation.从实体器官移植传播福氏耐格里虫的风险。
Am J Transplant. 2014 Jan;14(1):163-71. doi: 10.1111/ajt.12536. Epub 2013 Nov 26.
9
Balamuthia mandrillaris: in vitro interactions with selected protozoa and algae.曼氏迭宫绦虫：与选定原生动物和藻类的体外相互作用。
J Eukaryot Microbiol. 2013 Sep-Oct;60(5):448-54. doi: 10.1111/jeu.12052. Epub 2013 Jun 21.
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Central nervous system infection with Acanthamoeba in a malnourished child.一名营养不良儿童的中枢神经系统棘阿米巴感染。
BMJ Case Rep. 2012 Oct 24;2012:bcr2012007449. doi: 10.1136/bcr-2012-007449.

食脑变形虫：在大脑中的偏好部位及疾病转归

Brain-Eating Amoebae: Predilection Sites in the Brain and Disease Outcome.

作者信息

Ong Timothy Yu Yee, Khan Naveed Ahmed, Siddiqui Ruqaiyyah

机构信息

Department of Biological Sciences, School of Science and Technology, Sunway University, Bandar Sunway, Malaysia.

Department of Biological Sciences, School of Science and Technology, Sunway University, Bandar Sunway, Malaysia

出版信息

J Clin Microbiol. 2017 Jul;55(7):1989-1997. doi: 10.1128/JCM.02300-16. Epub 2017 Apr 12.

DOI:10.1128/JCM.02300-16
PMID:28404683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5483900/
Abstract

spp. and are causative agents of granulomatous amoebic encephalitis (GAE), while causes primary amoebic meningoencephalitis (PAM). PAM is an acute infection that lasts a few days, while GAE is a chronic to subacute infection that can last up to several months. Here, we present a literature review of 86 case reports from 1968 to 2016, in order to explore the affinity of these amoebae for particular sites of the brain, diagnostic modalities, treatment options, and disease outcomes in a comparative manner.

摘要

某些种类（spp.）以及其他种类是肉芽肿性阿米巴脑炎（GAE）的病原体，而另一种则会引发原发性阿米巴脑膜脑炎（PAM）。PAM是一种持续数天的急性感染，而GAE是一种慢性至亚急性感染，可持续长达数月。在此，我们对1968年至2016年的86例病例报告进行文献综述，以便以比较的方式探究这些阿米巴对脑特定部位的亲和性、诊断方法、治疗选择及疾病转归。