食脑变形虫：在大脑中的偏好部位及疾病转归
Brain-Eating Amoebae: Predilection Sites in the Brain and Disease Outcome.
作者信息
Ong Timothy Yu Yee, Khan Naveed Ahmed, Siddiqui Ruqaiyyah
机构信息
Department of Biological Sciences, School of Science and Technology, Sunway University, Bandar Sunway, Malaysia.
Department of Biological Sciences, School of Science and Technology, Sunway University, Bandar Sunway, Malaysia
出版信息
J Clin Microbiol. 2017 Jul;55(7):1989-1997. doi: 10.1128/JCM.02300-16. Epub 2017 Apr 12.
Abstract
spp. and are causative agents of granulomatous amoebic encephalitis (GAE), while causes primary amoebic meningoencephalitis (PAM). PAM is an acute infection that lasts a few days, while GAE is a chronic to subacute infection that can last up to several months. Here, we present a literature review of 86 case reports from 1968 to 2016, in order to explore the affinity of these amoebae for particular sites of the brain, diagnostic modalities, treatment options, and disease outcomes in a comparative manner.
摘要
某些种类（spp.）以及其他种类是肉芽肿性阿米巴脑炎（GAE）的病原体，而另一种则会引发原发性阿米巴脑膜脑炎（PAM）。PAM是一种持续数天的急性感染，而GAE是一种慢性至亚急性感染，可持续长达数月。在此，我们对1968年至2016年的86例病例报告进行文献综述，以便以比较的方式探究这些阿米巴对脑特定部位的亲和性、诊断方法、治疗选择及疾病转归。
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