• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

钯和铜催化合成新型胆烷氨基蒽醌钳形配体的方法。

Pd- and Cu-catalyzed approaches in the syntheses of new cholane aminoanthraquinone pincer-like ligands.

作者信息

Lukashev Nikolay V, Grabovyi Gennadii A, Erzunov Dmitry A, Kazantsev Alexey V, Latyshev Gennadij V, Averin Alexei D, Beletskaya Irina P

机构信息

Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991, Russia.

出版信息

Beilstein J Org Chem. 2017 Mar 20;13:564-570. doi: 10.3762/bjoc.13.55. eCollection 2017.

DOI:10.3762/bjoc.13.55
PMID:28405236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5372750/
Abstract

Cu- and Pd-catalyzed arylation of aminocholanes has been described for the first time. While this Cu-catalyzed protocol provides high yields in reactions of aminocholanes with iodoarenes, Pd catalysis was found to be preferable for the reactions of aminocholanes with dichloroanthraquinones. UV-vis titration of bis(cholanylamino)anthraquinones with a series of cations demonstrated their high binding affinity to Cu, Al, and Cr.

摘要

首次报道了铜和钯催化的氨基胆甾烷的芳基化反应。虽然这种铜催化的方法在氨基胆甾烷与碘代芳烃的反应中能提供高产率，但发现钯催化对于氨基胆甾烷与二氯蒽醌的反应更具优势。用一系列阳离子对双（胆甾基氨基）蒽醌进行紫外可见滴定，结果表明它们对铜、铝和铬具有高结合亲和力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/fd8d373a7cfa/Beilstein_J_Org_Chem-13-564-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/55852bf24c45/Beilstein_J_Org_Chem-13-564-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/5994d7978735/Beilstein_J_Org_Chem-13-564-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/323785cf5312/Beilstein_J_Org_Chem-13-564-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/12aa517964cf/Beilstein_J_Org_Chem-13-564-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/5574b05a1b23/Beilstein_J_Org_Chem-13-564-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/fd8d373a7cfa/Beilstein_J_Org_Chem-13-564-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/55852bf24c45/Beilstein_J_Org_Chem-13-564-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/5994d7978735/Beilstein_J_Org_Chem-13-564-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/323785cf5312/Beilstein_J_Org_Chem-13-564-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/12aa517964cf/Beilstein_J_Org_Chem-13-564-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/5574b05a1b23/Beilstein_J_Org_Chem-13-564-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12fb/5372750/fd8d373a7cfa/Beilstein_J_Org_Chem-13-564-g003.jpg

相似文献

1
Pd- and Cu-catalyzed approaches in the syntheses of new cholane aminoanthraquinone pincer-like ligands.钯和铜催化合成新型胆烷氨基蒽醌钳形配体的方法。
Beilstein J Org Chem. 2017 Mar 20;13:564-570. doi: 10.3762/bjoc.13.55. eCollection 2017.
2
Expanding Pd-catalyzed C-N bond-forming processes: the first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions.拓展钯催化的碳-氮键形成反应：芳基磺酸盐的首例酰胺化反应、水相胺化反应以及与铜催化反应的互补性
J Am Chem Soc. 2003 Jun 4;125(22):6653-5. doi: 10.1021/ja035483w.
3
Catalytic diamination of olefins via N-N bond activation.通过N-N键活化实现烯烃的催化双胺化反应。
Acc Chem Res. 2014 Dec 16;47(12):3665-78. doi: 10.1021/ar500344t. Epub 2014 Nov 17.
4
Design of New Ligands for the Palladium-Catalyzed Arylation of α-Branched Secondary Amines.用于钯催化α-支链仲胺芳基化反应的新型配体设计
Angew Chem Int Ed Engl. 2015 Jul 6;54(28):8259-62. doi: 10.1002/anie.201502626. Epub 2015 Jun 1.
5
Synthesis of unsymmetrical 2,2'-biindolyl derivatives by a Cu-catalyzed N-arylation/Pd-catalyzed direct arylation sequential process.通过 Cu 催化的 N-芳基化/Pd 催化的直接芳基化顺序反应合成不对称 2,2'-联吲哚衍生物。
J Org Chem. 2011 Feb 4;76(3):967-70. doi: 10.1021/jo101899a. Epub 2011 Jan 12.
6
Enantioselective synthesis of planar chiral ferrocenes via Pd(0)-catalyzed intramolecular direct C-H bond arylation.通过 Pd(0)催化的分子内直接 C-H 键芳基化反应对映选择性合成平面手性二茂铁。
J Am Chem Soc. 2014 Apr 2;136(13):4841-4. doi: 10.1021/ja500444v. Epub 2014 Mar 18.
7
BippyPhos: a single ligand with unprecedented scope in the Buchwald-Hartwig amination of (hetero)aryl chlorides.双膦配体 BippyPhos：在（杂）芳基氯化物的 Buchwald-Hartwig 胺化反应中具有前所未有的广泛应用。
Chemistry. 2013 Dec 2;19(49):16760-71. doi: 10.1002/chem.201302453. Epub 2013 Nov 4.
8
Direct bis-arylation of cyclobutanecarboxamide via double C-H activation: an auxiliary-aided diastereoselective Pd-catalyzed access to trisubstituted cyclobutane scaffolds having three contiguous stereocenters and an all-cis stereochemistry.通过双 C-H 活化实现环丁烷甲酰胺的直接双芳基化：一种辅助辅助的 Pd 催化的非对映选择性方法，用于构建具有三个连续立体中心和全顺式立体化学的三取代环丁烷支架。
J Org Chem. 2013 Dec 6;78(23):11911-34. doi: 10.1021/jo4019733. Epub 2013 Nov 20.
9
Mechanism of the Ullmann Biaryl Ether Synthesis Catalyzed by Complexes of Anionic Ligands: Evidence for the Reaction of Iodoarenes with Ligated Anionic Cu Intermediates.阴离子配体配合物催化的Ullmann 联苯醚合成反应机理：碘代芳烃与配体阴离子化 Cu 中间体反应的证据。
J Am Chem Soc. 2018 Jan 17;140(2):793-806. doi: 10.1021/jacs.7b11853. Epub 2018 Jan 5.
10
Mechanistic analysis of iridium(III) catalyzed direct C-H arylations: a DFT study.铱(III)催化的直接 C-H 芳基化反应的机理分析：DFT 研究。
Chemistry. 2011 Dec 2;17(49):13847-53. doi: 10.1002/chem.201101532. Epub 2011 Oct 27.

本文引用的文献

1
Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions.钯催化的碳-氮交叉偶联反应的应用
Chem Rev. 2016 Oct 12;116(19):12564-12649. doi: 10.1021/acs.chemrev.6b00512. Epub 2016 Sep 30.
2
Synthesis, spectroscopic and theoretical studies of new quasi-podands from bile acid derivatives linked by 1,2,3-triazole rings.通过1,2,3-三唑环连接的胆汁酸衍生物新型准穴状配体的合成、光谱及理论研究
Molecules. 2014 Feb 24;19(2):2557-70. doi: 10.3390/molecules19022557.
3
Synthesis of a bile acid-based click-macrocycle and its application in selective recognition of chloride ion.
基于胆汁酸的点击大环的合成及其对氯离子的选择性识别应用。
J Org Chem. 2011 Nov 4;76(21):9086-9. doi: 10.1021/jo201161n. Epub 2011 Sep 30.
4
Rational design of aminoanthraquinones for colorimetric detection of heavy metal ions in aqueous solution.基于结构的氨基蒽醌衍生物的设计及其用于水溶液中重金属离子的比色检测。
Dalton Trans. 2011 Oct 28;40(40):10491-502. doi: 10.1039/c1dt10677e. Epub 2011 Aug 9.
5
Steroid-based anion receptors and transporters.基于甾体的阴离子受体和转运体。
Chem Soc Rev. 2010 Oct;39(10):3633-47. doi: 10.1039/b926225n. Epub 2010 Aug 11.
6
1,2,3-Triazole-containing molecular pockets derived from cholic acid: the influence of structure on host-guest coordination properties.含 1,2,3-三氮唑分子口袋衍生自胆酸：结构对主客体配位性质的影响。
Langmuir. 2010 Aug 17;26(16):13415-21. doi: 10.1021/la102158a.
7
From cholapod to cholaphane transmembrane anion carriers: accelerated transport through binding site enclosure.从 CholaPod 到 CholaPhane 阴离子跨膜载体：通过结合位点封闭实现快速转运。
Chem Commun (Camb). 2010 Apr 7;46(13):2227-9. doi: 10.1039/b927005a. Epub 2010 Feb 25.
8
Diaminoanthraquinone-linked polyazamacrocycles: efficient and simple colorimetric sensor for lead ion in aqueous solution.二氨基蒽醌连接的多氮杂大环化合物：用于水溶液中铅离子的高效简便比色传感器。
Org Lett. 2009 Feb 19;11(4):987-90. doi: 10.1021/ol802926m.
9
Molecular umbrella transport: exceptions to the classic size/lipophilicity rule.分子伞运输：经典尺寸/亲脂性规则的例外情况。
J Am Chem Soc. 2009 Feb 4;131(4):1338-9. doi: 10.1021/ja806476t.
10
Role of bile acids and bile acid receptors in metabolic regulation.胆汁酸及胆汁酸受体在代谢调节中的作用
Physiol Rev. 2009 Jan;89(1):147-91. doi: 10.1152/physrev.00010.2008.