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[大鼠幼崽离体脊髓中运动神经元相互作用的机制]

[Mechanisms of motor neuron interaction in the isolated spinal cord of rat pups].

作者信息

Karamian O A, Kozhanov V M, Chmykhova N M

出版信息

Neirofiziologiia. 1988;20(2):243-50.

PMID:2840585
Abstract

Interactions between lumbar motoneurons were studied by intracellular recording of responses to stimulation of ventral roots and intracellular HRP injection in isolated spinal cord preparations of immature (9-14 days old) rats. Ventral root-evoked electrotonic potentials in individual motoneurons were due to interconnections with few other motoneurons and could not elicit spike potentials. Direct chemical excitatory interactions of motoneurons were also found which may occur via axon collaterals. Differences between individual motoneurons in the mode of responses to ventral root stimulation, probably, depend on their functional specialization.

摘要

通过在未成熟(9 - 14日龄)大鼠的离体脊髓标本中对腹根刺激的反应进行细胞内记录以及细胞内注射辣根过氧化物酶(HRP),研究了腰段运动神经元之间的相互作用。单个运动神经元中腹根诱发的电紧张电位是由于与少数其他运动神经元的相互连接所致,并且不能引发动作电位。还发现了运动神经元之间可能通过轴突侧支发生的直接化学性兴奋相互作用。单个运动神经元对腹根刺激的反应模式差异可能取决于它们的功能特化。

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