King R H, Llewelyn J G, Thomas P K, Gilbey S G, Watkins P J
Department of Neurological Science, Royal Free Hospital School of Medicine, London, UK.
Neuropathol Appl Neurobiol. 1988 Mar-Apr;14(2):105-23. doi: 10.1111/j.1365-2990.1988.tb00874.x.
A study of the occurrence of extracellular deposits of calcium in the perineurium of the human sural nerve demonstrated that there is a higher incidence in abnormal nerves than in normal material and that, of the conditions examined, nerves from cases of diabetic neuropathy showed the greatest incidence of calcification. It seems likely that the process of calcification is similar to that operating in other tissues, with deposition on matrix vesicles or lipid droplets, probably derived from the perineurial cells. The increased incidence in diabetic neuropathy is presumably related to metabolic abnormality consequent upon the diabetic state.
一项关于人腓肠神经神经束膜中细胞外钙沉积发生情况的研究表明，异常神经中的发生率高于正常组织，并且在所检查的病症中，糖尿病性神经病变病例的神经钙化发生率最高。钙化过程似乎与其他组织中的过程相似，钙沉积在基质小泡或脂滴上，这些小泡或脂滴可能源自神经束膜细胞。糖尿病性神经病变中发生率的增加大概与糖尿病状态导致的代谢异常有关。
