Osunde O D, Anyanechi C E, Bassey G O
Department of Dental Surgery, University of Calabar Teaching Hospital, University of Calabar, Calabar, Nigeria.
Niger J Clin Pract. 2017 Apr;20(4):470-473. doi: 10.4103/1119-3077.180064.
Chlorhexidine mouth rinses have a proven efficacy for the prevention of alveolar osteitis after third molar surgery. This study compares the efficacy of warm saline rinse, a component of postextraction instructions, with that of chlorhexidine in our institution over a period of 2 years.
Apparently healthy patients who were referred to the Oral Surgery Clinic of our institution, with an indication for surgical extraction of lower third molar were prospectively, consecutively, and uniformly randomized into warm saline and chlorhexidine groups. The experimental group (n = 50/100) were instructed to gargle twice daily with warm saline, whereas the chlorhexidine group (n = 50/100) were instructed to gargle with 0.12% chlorhexidine. Information on demographic, types and level of impaction, indications for extraction, and development of alveolar osteitis were obtained and analyzed. Comparative statistics were done using Pearson's Chi-square, Fisher's exact, or Mann-Whitney U-tests as appropriate. P <0.05 was considered statistically significant.
The demographic, types and level of impaction as well as indications for extractions were comparable between the study groups (P > 0.05). The overall prevalence of alveolar osteitis was 5%. There was no statistically significant difference between application of warm saline and 0.12% chlorhexidine rinse with respect to the development of alveolar osteitis (P = 0.648).
Warm saline mouth rinse is equally as effective as chlorhexidine mouth rinse, as prophylaxis against prevention of alveolar osteitis after third molar surgery.
洗必泰漱口水在预防第三磨牙拔除术后牙槽骨炎方面已被证实有效。本研究比较了我院在2年时间里，拔牙后医嘱中的温盐水漱口与洗必泰漱口水的预防效果。
前瞻性、连续性且均匀地将我院口腔外科门诊中，有手术拔除下颌第三磨牙指征的表面健康患者随机分为温盐水组和洗必泰组。实验组（n = 50/100）被指导每天用温盐水漱口两次，而洗必泰组（n = 50/100）被指导用0.12%的洗必泰漱口。收集并分析了患者的人口统计学信息、阻生类型和程度、拔牙指征以及牙槽骨炎的发生情况。根据情况使用Pearson卡方检验、Fisher精确检验或Mann-Whitney U检验进行比较统计。P <0.05被认为具有统计学意义。
研究组之间的人口统计学、阻生类型和程度以及拔牙指征具有可比性（P > 0.05）。牙槽骨炎的总体患病率为5%。在牙槽骨炎的发生方面，温盐水漱口和0.12%洗必泰漱口之间没有统计学显著差异（P = 0.648）。
作为预防第三磨牙拔除术后牙槽骨炎的措施，温盐水漱口与洗必泰漱口同样有效。
