食管癌切除术中胸导管结扎对D-木糖吸收的影响
Effect of Ligation of the Thoracic Duct During Oesophagectomy on the Absorption of D-xylose.
作者信息
Yang Rui -Feng, Jiang Zhong -Min, Zhang Run -Qi, Yu Bing, Wang Xiao -Hong, Wang Peng
机构信息
Department of Thoracic Surgery, Qianfoshan Hospital of Shandong Province, Shandong University, Ji'nan, Shandong 250012, China.
Department of Thoracic Surgery, Tai'an City Central Hospital, Tai'an, Shandong 271000, China.
出版信息
J Coll Physicians Surg Pak. 2017 Mar;27(3):153-156.
OBJECTIVE
To assess if prophylactic thoracic duct ligation during oesophagectomy influences the absorptive function of oesophageal cancer patients.
STUDY DESIGN
Randomized controlled trial.
PLACE AND DURATION OF STUDY
Department of Thoracic Surgery, Tai'an City Central Hospital, Tai'an, from August 2014 to December 2015.
METHODOLOGY
Based on the management of the thoracic duct during oesophagectomy, 60 patients were randomized into two groups. D-xylose absorption test was used to evaluate the absorptive function. The two-independent-samples t-test was employed for statistical analysis with statistical significance at p < 0.05.
RESULTS
The serum D-xylose concentration of ligation-group was significantly lower than that of no-ligation group on the first day after operation, (t=2.82, p=0.0066). However, there was no significant differences between them even before operation (t=1.34, p=0.1849).
CONCLUSION
Ligation of the thoracic duct during oesophagectomy immediately affected the absorption of D-xylose, which may lead to malabsorption in the long run.
目的
评估食管癌切除术中预防性胸导管结扎是否会影响食管癌患者的吸收功能。
研究设计
随机对照试验。
研究地点和时间
2014年8月至2015年12月，泰安市中心医院胸外科。
方法
根据食管癌切除术中胸导管的处理方式，将60例患者随机分为两组。采用D-木糖吸收试验评估吸收功能。采用两独立样本t检验进行统计分析，p<0.05具有统计学意义。
结果
结扎组术后第1天血清D-木糖浓度显著低于未结扎组（t=2.82，p=0.0066）。然而，术前两组之间也无显著差异（t=1.34，p=0.1849）。
结论
食管癌切除术中结扎胸导管会立即影响D-木糖的吸收，长期来看可能导致吸收不良。
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