Him Mali, Meier Maggie, Mehta Vikas
Mount Sinai Hospital, Chicago, IL, USA.
St. Luke's Hospital St. Louis, MO, USA.
Case Rep Oncol Med. 2017;2017:4296802. doi: 10.1155/2017/4296802. Epub 2017 Mar 16.
Malignant plasma cell proliferation can be presented as part of disseminated disease of multiple myeloma, as solitary plasmacytoma of bone, or in soft tissue as extramedullary plasmacytoma. Extramedullary plasmacytomas represented approximately 3% of all plasma cell proliferation. Approximately 80% of extramedullary plasmacytomas occur in the head and neck region while the other 4% occur in the skin and to a lesser extent in the lip. In this paper, we report a rare case of primary cutaneous plasmacytoma involving the lip in a 65-year-old male. The patient presented with a nonhealing lower lip sore for the past 3 years. Upon further workup, there was no evidence of multiple myeloma or light chain disease. The patient was treated with radiation therapy and his last follow-up revealed no evidence of multiple myeloma or light chain disease.
恶性浆细胞增殖可表现为多发性骨髓瘤播散性疾病的一部分、骨孤立性浆细胞瘤或软组织中的髓外浆细胞瘤。髓外浆细胞瘤约占所有浆细胞增殖的3%。约80%的髓外浆细胞瘤发生在头颈部区域，另有4%发生在皮肤，唇部较少见。在本文中，我们报告了一例65岁男性唇部原发性皮肤浆细胞瘤的罕见病例。患者在过去3年中下唇出现不愈合溃疡。进一步检查后，未发现多发性骨髓瘤或轻链病的证据。患者接受了放射治疗，其最后一次随访显示无多发性骨髓瘤或轻链病的证据。
