IEEE Trans Ultrason Ferroelectr Freq Control. 2017 Jul;64(7):1034-1044. doi: 10.1109/TUFFC.2017.2692558. Epub 2017 Apr 7.
Radio-frequency ablation (RFA) is used to locally disrupt electrical propagation in myocardium and treat arrhythmias, and direct visualization of ablation lesions by acoustic radiation force methods may benefit RFA procedures. This paper compares four imaging modalities, B-mode, acoustic radiation force impulse (ARFI), single-track-location shear wave elasticity imaging (STL-SWEI), and multiple-track-location shear wave elasticity imaging (MTL-SWEI), in their ability to resolve RFA lesions in four ex vivo experiments. Ablation lesions are shown to be marked by at least a local halving of ARFI displacements and doubling of shear wave speeds. In a controlled ablation of ex vivo porcine and canine cardiac tissue, STL-SWEI and ARFI are shown to have a similar CNR, better than MTL-SWEI and B-mode. The SWEI modalities are demonstrated to have improved imaging of distal lesion boundaries. Gaps smaller than 5 mm are visualized in ablation lines made of discretely spaced ablations, and complex structures are reconstructed through depth in an "x" ablation experiment. Scans of suspended atria show increased noise, but successfully visualize ablations in ARFI, MTL-SWEI, and STL-SWEI.
射频消融(RFA)用于局部破坏心肌中的电传播并治疗心律失常,而通过声辐射力方法直接可视化消融损伤可能有益于 RFA 程序。本文比较了四种成像模式,即 B 模式、声辐射力脉冲(ARFI)、单轨迹定位剪切波弹性成像(STL-SWEI)和多轨迹定位剪切波弹性成像(MTL-SWEI),在四个离体实验中它们在分辨 RFA 损伤方面的能力。消融损伤至少表现为 ARFI 位移减半和剪切波速度增加一倍。在离体猪和犬心脏组织的受控消融中,STL-SWEI 和 ARFI 的 CNR 相似,优于 MTL-SWEI 和 B 模式。SWEI 模式被证明可以改善远端损伤边界的成像。离散消融线形成的消融线中可以观察到小于 5mm 的间隙,并且在“x”消融实验中通过深度重建复杂结构。悬浮心房的扫描显示出增加的噪声,但在 ARFI、MTL-SWEI 和 STL-SWEI 中成功地可视化了消融。