Vasiu Iosif, Dąbrowski Roman, Martinez-Subiela Silvia, Ceron Jose J, Wdowiak Anna, Pop Raul Alexandru, Brudaşcă Florinel Gheorghe, Pastor Josep, Tvarijonaviciute Asta
Department and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 3-5 Calea Mănăştur St, 400372 Cluj-Napoca, Romania.
Department and Clinic of Animal Reproduction, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 30 Gleboka St, 20-612 Lublin, Poland.
Vet Immunol Immunopathol. 2017 Apr;186:41-44. doi: 10.1016/j.vetimm.2017.02.005. Epub 2017 Feb 27.
Presence of mastitis in lactating bitches can become life threatening for both the bitch and pups. The aim of the present study was to evaluate a possible utility of C-reactive protein (CRP) in both milk and serum for canine mastitis diagnosis. Our study showed that milk CRP levels ranged between 0.1 and 4.9μg/mL and from 0.3 to 40.0μg/mL in healthy and diseased bitches (P<0.01), respectively, while serum CRP levels ranged between 2.0 and 8.6μg/mL and between 0.3 and 162.3μg/mL in healthy and diseased bitches (P<0.01), respectively. Milk and serum CRP levels were higher in both clinical and subclinical mastitis when compared with healthy controls (P<0.05 in all cases). However, no significant differences were recorded in CRP concentrations between clinical and subclinical cases. Based on these results, it could be concluded that serum and milk CRP could be useful in order to diagnose canine mastitis.
哺乳期母犬患乳腺炎可能会对母犬和幼犬的生命构成威胁。本研究的目的是评估C反应蛋白（CRP）在乳汁和血清中对犬乳腺炎诊断的潜在效用。我们的研究表明，健康母犬和患病母犬的乳汁CRP水平分别在0.1至4.9μg/mL和0.3至40.0μg/mL之间（P<0.01），而血清CRP水平分别在2.0至8.6μg/mL和0.3至162.3μg/mL之间（P<0.01）。与健康对照组相比，临床和亚临床乳腺炎的乳汁和血清CRP水平均较高（所有情况P<0.05）。然而，临床病例和亚临床病例之间的CRP浓度没有显著差异。基于这些结果，可以得出结论，血清和乳汁CRP可用于诊断犬乳腺炎。
