Jakhetiya Ashish, Garg Pankaj Kumar, Pandey Rambha, Ramanathan Palaniappan, Kumar Sunil, Nath Debojit, Pandey Durgatosh
Department of Surgical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, New Delhi, India.
South Asian J Cancer. 2017 Jan-Mar;6(1):6-10. doi: 10.4103/2278-330X.202568.
Bronchopulmonary carcinoids are uncommon tumors with relatively indolent biological behavior but a distinct malignant potential. Surgery is the mainstay of treatment. Our aim was to study preoperative characteristics, surgical approaches, and outcome in patients with bronchopulmonary carcinoid tumors.
This retrospective study was done in the Department of Surgical Oncology of a Tertiary Teaching Hospital of North India. The case records of all the patients who underwent surgical treatment for lung neoplasms and were diagnosed to have bronchopulmonary carcinoids were reviewed. Details concerning the clinical presentation, preoperative therapy, operative procedure, postoperative complications, and outcome were retrieved from the case records.
Sixteen patients who underwent surgical treatment were found to have bronchopulmonary carcinoids on histopathological examination. The median age of the patients was 34 years (range 18-62 years). There were 11 men and five women. All patients were symptomatic, and the median duration of symptoms was 12 months (range 6-72 months) before presentation. Six patients had received antitubercular treatment before presentation, and one patient had been treated with chemotherapy due to misdiagnosis. Surgical procedures included six pneumonectomies (one with carinoplasty), four bilobectomies, three lobectomies, and three bronchoplastic procedures (two with lobectomy and one with bilobectomy). There was no postoperative mortality; three patients had morbidity in the form of lobar collapse, prolonged pleural collection, and surgical site infection. With a median follow-up time of 11 months (range 2-85 months), all the 16 patients are alive and disease-free.
Delayed presentation and misdiagnosis of bronchial carcinoid are major concerns in North India. Adequate surgical resection can be performed without undue morbidity and is associated with good long-term results.
支气管肺类癌是罕见肿瘤，具有相对惰性的生物学行为，但有明显的恶性潜能。手术是主要治疗方法。我们的目的是研究支气管肺类癌肿瘤患者的术前特征、手术方式及预后。
这项回顾性研究在印度北部一家三级教学医院的外科肿瘤学部门进行。回顾了所有接受肺部肿瘤手术治疗且被诊断为支气管肺类癌的患者的病例记录。从病例记录中获取了有关临床表现、术前治疗、手术过程、术后并发症及预后的详细信息。
16例接受手术治疗的患者经组织病理学检查确诊为支气管肺类癌。患者的中位年龄为34岁（范围18 - 62岁）。男性11例，女性5例。所有患者均有症状，症状出现至就诊的中位持续时间为12个月（范围6 - 72个月）。6例患者在就诊前接受过抗结核治疗，1例患者因误诊接受过化疗。手术方式包括6例全肺切除术（1例伴有隆突成形术）、4例双叶切除术、3例肺叶切除术和3例支气管成形术（2例伴有肺叶切除术，1例伴有双叶切除术）。无术后死亡；3例患者出现并发症，表现为肺叶萎陷、胸腔积液持续时间延长和手术部位感染。中位随访时间为11个月（范围2 - 85个月），16例患者均存活且无疾病复发。
在印度北部，支气管类癌的就诊延迟和误诊是主要问题。可以进行充分的手术切除，且不会有过多的并发症，并且长期效果良好。
