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小样本量混淆了对运动的心脏代谢反应的理解。

Small Sample Sizes Confound Understanding of Cardiometabolic Responses to Exercise.

作者信息

Pescatello Linda S, Corso Lauren M L, MacDonald Hayley V, Thompson Paul D, Taylor Beth A, Panza Gregory A, Zaleski Amanda L, Johnson Blair T, Chen Ming-Hui

机构信息

1Departments of Kinesiology; 2Psychological Sciences; 3Statistics; 4Institute for Collaboration on Health, Intervention and Policy (InCHIP), University of Connecticut, Storrs CT; 5Department of Kinesiology, The University of Alabama, Tuscaloosa, AL; and 6Department of Cardiology, Henry Low Heart Center, Hartford Hospital, Hartford CT.

出版信息

Exerc Sport Sci Rev. 2017 Jul;45(3):173-180. doi: 10.1249/JES.0000000000000115.

DOI:10.1249/JES.0000000000000115
PMID:28419004
Abstract

Considerable variability exists in the cardiometabolic disease biomarker response to exercise. We propose that a major contributor to this heterogeneity is underpowered studies due to small sample sizes. To test our hypothesis, we conducted a systematic review to identify meta-analyses/reviews of randomized controlled trials (RCT) and RCT that examined the cardiometabolic disease biomarker response to aerobic and resistance exercise.

摘要

心血管代谢疾病生物标志物对运动的反应存在相当大的变异性。我们认为,造成这种异质性的一个主要因素是样本量小导致研究效能不足。为了验证我们的假设,我们进行了一项系统综述,以确定对有氧运动和抗阻运动的心血管代谢疾病生物标志物反应进行检验的随机对照试验(RCT)的荟萃分析/综述以及RCT。

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