Xin Mintong, Guo Shanshan, Zhang Wenjuan, Geng Zhufeng, Liang Junyu, Du Shushan, Deng Zhiwei, Wang Yongyan
Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China.
Analytical and Testing Center, Beijing Normal University, Beijing 100875, China.
Molecules. 2017 Apr 18;22(4):647. doi: 10.3390/molecules22040647.
has been confirmed to possess bioactivities against some pests. In this work, a sample was obtained from rhizomes by supercritical fluid CO₂ extraction (SFE). According to GC-MS analysis, the main chemical components for SFE-sample included benzylacetone (26.77%), 1,7-diphenyl-5-hydroxy-3-heptanone (17.78%), guaiacylacetone (10.03%) and benzenepropanal (7.42%). The essential oil of rhizomes (LD = 20.71 μg/adult) exhibited more contact toxicity than SFE extract (LD = 82.72 μg/adult) against . From SFE extracts, one new compound, 1-phenyl-4-(16,17-dimethyl-9,13-octadiene)-5-isopentenyl-7-(4"-methoxyl-3"-hydroxyl-phenyl)-3-heptanone (), together with five known compounds identified as 5-hydroxy-1,7-diphenyl-3-heptanone (), 1,7-diphenyl-4-hepten-3-one (), galangin (), galangin-3-methyl ether () and pinocembrin (), were isolated and their feeding deterrent activities against adults were assessed. It was found that compounds - had feeding deterrent activities against with feeding deterrent indices of 18.21%, 18.94%, 19.79%, 26.99%, 20.34%, and 35.81%, respectively, at the concentration of 1500 ppm. Hence, the essential oil and SFE extracts/compounds of rhizomes represent promising alternatives in the control of adults.
已证实具有针对某些害虫的生物活性。在本研究中，通过超临界流体CO₂萃取（SFE）从根茎中获得了一个样品。根据气相色谱 - 质谱分析，SFE样品的主要化学成分包括苄基丙酮（26.77%）、1,7 - 二苯基 - 5 - 羟基 - 3 - 庚酮（17.78%）、愈创木基丙酮（10.03%）和苯丙醛（7.42%）。根茎的精油（LD = 20.71μg/成虫）对……表现出比SFE提取物（LD = 82.72μg/成虫）更强的接触毒性。从SFE提取物中，分离出一种新化合物1 - 苯基 - 4 -（16,17 - 二甲基 - 9,13 - 十八碳二烯）- 5 - 异戊烯基 - 7 -（4″ - 甲氧基 - 3″ - 羟基 - 苯基）- 3 - 庚酮（），以及五种已知化合物，分别鉴定为5 - 羟基 - 1,7 - 二苯基 - 3 - 庚酮（）、1,7 - 二苯基 - 4 - 庚烯 - 3 - 酮（）、高良姜素（）、高良姜素 - 3 - 甲醚（）和松属素（），并评估了它们对成虫的拒食活性。发现在1500 ppm浓度下，化合物 - 对……具有拒食活性，拒食指数分别为18.21%、18.94%、19.79%、26.99%、20.34%和35.81%。因此，根茎的精油和SFE提取物/化合物在控制成虫方面代表了有前景的替代物。
