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Physical and Cognitive Stimulation Using an Exergame in Subjects with Normal Aging, Mild and Moderate Cognitive Impairment.在正常衰老、轻度和中度认知障碍受试者中使用运动游戏进行身体和认知刺激
J Alzheimers Dis. 2016 Jun 30;53(4):1299-314. doi: 10.3233/JAD-160268.
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Memantine and donepezil: a fixed drug combination for the treatment of moderate to severe Alzheimer's dementia.美金刚与多奈哌齐:用于治疗中重度阿尔茨海默病痴呆的固定剂量复方制剂。
Drugs Today (Barc). 2016 Apr;52(4):239-48. doi: 10.1358/dot.2016.52.4.2479357.
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Persons With Advanced Alzheimer's Disease Engage in Mild Leg Exercise Supported by Technology-Aided Stimulation and Prompts.患有晚期阿尔茨海默病的人在技术辅助刺激和提示的支持下进行轻度腿部锻炼。
Behav Modif. 2017 Jan 1;41(1):3-20. doi: 10.1177/0145445516649581. Epub 2016 May 10.
5
Technology-Aided Programs to Support Positive Verbal and Physical Engagement in Persons with Moderate or Severe Alzheimer's Disease.技术辅助项目,以支持中度或重度阿尔茨海默病患者进行积极的言语和身体互动。
Front Aging Neurosci. 2016 Apr 21;8:87. doi: 10.3389/fnagi.2016.00087. eCollection 2016.
6
Treatment of Cognitive Deficits in Alzheimer's disease: A psychopharmacological review.阿尔茨海默病认知缺陷的治疗:一项精神药理学综述。
Psychiatr Danub. 2016 Mar;28(1):2-12.
7
Why has therapy development for dementia failed in the last two decades?为什么在过去的二十年中,痴呆症的治疗方法研发失败了?
Alzheimers Dement. 2016 Jan;12(1):60-4. doi: 10.1016/j.jalz.2015.12.003. Epub 2015 Dec 19.
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Exercise as a Polypill for Chronic Diseases.运动作为治疗慢性病的复方制剂。
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Effects of Physical Exercise on Health and Well-Being of Individuals Living With a Dementia in Nursing Homes: A Systematic Review.体育锻炼对养老院中患有痴呆症个体的健康和福祉的影响:系统评价。
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Using simple technology to prompt multistep tasks in the home for people with dementia: An exploratory study comparing prompting formats.使用简单技术促使痴呆症患者在家中完成多步骤任务:一项比较提示形式的探索性研究。
Dementia (London). 2017 May;16(4):424-442. doi: 10.1177/1471301215602417. Epub 2015 Sep 30.

通过一项技术辅助计划支持中重度阿尔茨海默病患者进行简单活动参与。

Supporting Simple Activity Engagement in Persons With Moderate to Severe Alzheimer's Disease Through a Technology-Aided Program.

作者信息

Lancioni Giulio E, Singh Nirbhay N, O'Reilly Mark F, Sigafoos Jeff, D'Amico Fiora, Pinto Katia, Chiapparino Claudia

机构信息

1 Department of Neuroscience and Sense Organs, University of Bari, Bari, Italy.

2 Medical College of Georgia, Augusta University, Augusta, GA, USA.

出版信息

Am J Alzheimers Dis Other Demen. 2017 May;32(3):137-144. doi: 10.1177/1533317517698793. Epub 2017 Mar 21.

DOI:10.1177/1533317517698793
PMID:28423935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10852665/
Abstract

OBJECTIVES

These 2 studies assessed a technology-aided program to support mild physical exercise or simple occupational activity in participants with moderate to severe Alzheimer's disease.

METHODS

Study 1 included 11 participants who were to perform a leg-raising response. Study 2 included 10 participants who were to sort objects into different containers. The program ensured that they received positive stimulation contingent on the responses and reminders/prompts after periods of nonresponding. Each study was carried out according to a nonconcurrent multiple baseline design across participants.

RESULTS

The program was successful in supporting mild physical exercise and activity with objects in the 2 groups of participants, respectively. The participants also showed signs of positive involvement (eg, smiles and verbalizations) during the sessions. Moreover, staff personnel rated the program and its impact positively.

CONCLUSION

The program may be considered a practical resource for supporting positive engagement in persons with moderate to severe Alzheimer's disease.

摘要

目的

这两项研究评估了一项技术辅助项目,以支持中度至重度阿尔茨海默病患者进行轻度体育锻炼或简单的职业活动。

方法

研究1纳入了11名要进行抬腿反应的参与者。研究2纳入了10名要将物品分类到不同容器中的参与者。该项目确保他们在做出反应后能得到积极刺激,并在无反应一段时间后得到提醒/提示。每项研究均根据参与者的非同期多重基线设计进行。

结果

该项目分别成功地支持了两组参与者进行轻度体育锻炼和物品相关活动。参与者在活动期间也表现出积极参与的迹象(如微笑和发声)。此外,工作人员对该项目及其影响给予了积极评价。

结论

该项目可被视为支持中度至重度阿尔茨海默病患者积极参与的实用资源。