1 Uskudar University, Turkey.
2 Marmara University, Turkey.
J Atten Disord. 2018 May;22(7):694-702. doi: 10.1177/1087054717703188. Epub 2017 Apr 19.
In this study, we aimed to explore how cues signaling rewards and feedbacks about rewards are processed in ADHD.
Inside the scanner, 16 healthy children and 19 children with ADHD completed a spatial attention paradigm where cues informed about the availability of reward and feedbacks were provided about the earned reward.
In ventral anterior thalamus (VA), the controls exhibited greater activation in response to reward-predicting cues, as compared with no-reward cues, whereby in the ADHD group, the reverse pattern was observed (nonreward > reward). For feedbacks; absence of rewards produced greater activation than presence in the left caudate and frontal eye field for the control group, whereas for the ADHD group, the reverse pattern was again observed (reward > nonreward).
The present findings indicate that ADHD is associated with difficulty integrating reward contingency information with the orienting and regulatory phases of attention.
本研究旨在探讨 ADHD 中与奖励相关的线索和反馈信号是如何被加工的。
在扫描仪内，16 名健康儿童和 19 名 ADHD 儿童完成了一个空间注意范式，线索提示奖励的可获得性，反馈则提供关于所获得奖励的信息。
在腹侧前丘脑（VA）中，对照组对奖励预测线索的反应比无奖励线索更强，而 ADHD 组则观察到相反的模式（非奖励>奖励）。对于反馈，对照组中左尾状核和额眼区的无奖励产生的激活大于有奖励，而 ADHD 组再次观察到相反的模式（奖励>无奖励）。
本研究结果表明，ADHD 与难以将奖励关联性信息与注意的定向和调节阶段整合有关。
