de Jong T A, Wermenbol A G, van der Avoort H G, Wigand R
Abteilung für Virologie, Universittskliniken, Homburg/Saar, Federal Republic of Germany.
J Med Virol. 1988 May;25(1):77-83. doi: 10.1002/jmv.1890250111.
Seventy-six strains of adenovirus type 37 (AV37), isolated during a period of 10 years from 73 patients on three continents, were analysed with eight DNA restriction endonucleases. Strains identical with the prototype (56 strains) prevailed; four deviating genome types were found, which differed only slightly from the prototype, with one exception. Half of the strains were tested in detail by neutralisation and haemagglutination inhibition. Minor differences in neutralisation were not reflected by differences in DNA restriction patterns. In comparison to genome types of other subgenera, field strains of adenovirus 37 showed only a moderate genetic variability.
对从三大洲73名患者中在10年期间分离出的76株37型腺病毒（AV37），用8种DNA限制性内切酶进行了分析。与原型相同的菌株（56株）占主导；发现了4种偏离的基因组类型，它们与原型仅略有不同，只有一个例外。一半的菌株通过中和试验和血凝抑制试验进行了详细检测。中和试验中的微小差异并未反映在DNA限制性图谱的差异上。与其他亚属的基因组类型相比，37型腺病毒的现场菌株仅表现出中等程度的遗传变异性。
