Zurstrassen Charles Edouard, Bitencourt Almir Galvão Vieira, Guimaraes Marcos Duarte, Cavalcante Aline Cristine Barbosa Santos, Tyng Chiang Jeng, Amoedo Mauricio Kauark, Matsushita Junior João Paulo Kawaoka, Szklaruk Janio, Marchiori Edson, Chojniak Rubens
Head of the Department of Interventional Radiology, A.C.Camargo Cancer Center, São Paulo, SP, Brazil.
Staff Physician in the Department of Imaging, A.C.Camargo Cancer Center, São Paulo, SP, Brazil.
Radiol Bras. 2017 Mar-Apr;50(2):97-102. doi: 10.1590/0100-3984.2015.0183.
This study aimed to compare two self-expanding stents, a nitinol stent and an elgiloy stent, both placed percutaneously, in terms of their efficacy in palliating inoperable malignant biliary obstruction.
We retrospectively investigated 99 patients with unresectable malignant biliary obstruction treated with percutaneous placement of a self-expanding metallic stent at our institution between May 2007 and January 2010. Serum bilirubin and liver enzyme levels were measured before and 30 days after stenting. For all procedures using elgiloy or nitinol stents, stent occlusion and patient survival rates were calculated using Kaplan-Meyer analysis.
All of the patients showed clinical improvement after stent placement, with no difference between the two groups. In both groups, the occlusion-free survival rate was 67% at 30 days, 37% at 90 days, 25% at 180 days, and 10% at 360 days, with no significant difference in relation to the type of stent.
The two stents evaluated showed comparable efficacy for the percutaneous treatment of unresectable biliary malignancy, with good clinical results.
本研究旨在比较两种经皮置入的自膨式支架，即镍钛合金支架和埃尔吉洛伊耐蚀合金支架，在缓解不可手术切除的恶性胆道梗阻方面的疗效。
我们回顾性研究了2007年5月至2010年1月期间在我院接受经皮自膨式金属支架置入治疗的99例不可切除恶性胆道梗阻患者。在支架置入前及置入后30天测量血清胆红素和肝酶水平。对于所有使用埃尔吉洛伊耐蚀合金或镍钛合金支架的手术，使用Kaplan - Meyer分析计算支架闭塞率和患者生存率。
所有患者在支架置入后均显示临床改善，两组之间无差异。两组在30天时无闭塞生存率为67%，90天时为37%，180天时为25%，360天时为10%，与支架类型无关，无显著差异。
所评估的两种支架在经皮治疗不可切除的胆道恶性肿瘤方面显示出相当的疗效，临床效果良好。
