Semkina A S, Abakumov M A, Grinenko N F, Lipengolts A A, Nukolova N V, Chekhonin V P
N. I. Pirogov Russian National Research Medical University, Moscow, Russia.
MISiS National Research Technological University, Moscow, Russia.
Bull Exp Biol Med. 2017 Apr;162(6):808-811. doi: 10.1007/s10517-017-3718-x. Epub 2017 Apr 21.
We studied the possibility of using BSA-coated magnetic iron oxide nanoparticles for magnetic resonance imaging diagnosis of C6 glioblastoma, 4T1 mammary adenocarcinoma, and RS-1 hepatic mucous carcinoma. In all three cases, magnetic nanoparticles accumulated in the tumor and its large vessels. Magnetic resonance imaging with contrast agent allows visualization of the tumor tissue and its vascularization.
我们研究了使用牛血清白蛋白包被的磁性氧化铁纳米颗粒用于C6胶质母细胞瘤、4T1乳腺腺癌和RS-1肝黏液癌磁共振成像诊断的可能性。在所有这三种情况下，磁性纳米颗粒都在肿瘤及其大血管中聚集。使用造影剂的磁共振成像能够显示肿瘤组织及其血管分布情况。
