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Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors.

作者信息

Zhu Jie, Ming Chang, Fu Xin, Duan Yaou, Hoang Duc Anh, Rutgard Jeffrey, Zhang Runze, Wang Wenqiu, Hou Rui, Zhang Daniel, Zhang Edward, Zhang Charlotte, Hao Xiaoke, Xiong Wenjun, Zhang Kang

机构信息

Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.

Shiley Eye Institute, Institute for Engineering in Medicine, Center for Genetic Therapy at Institute for Genomic Medicine, University of California, San Diego, La Jolla, California 92093, USA.

出版信息

Cell Res. 2017 Jun;27(6):830-833. doi: 10.1038/cr.2017.57. Epub 2017 Apr 21.

DOI:10.1038/cr.2017.57
PMID:28429769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5518875/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b3c/5518875/a5841314c33b/cr201757f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b3c/5518875/a5841314c33b/cr201757f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b3c/5518875/a5841314c33b/cr201757f1.jpg

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本文引用的文献

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2
Lens regeneration using endogenous stem cells with gain of visual function.利用具有视觉功能恢复的内源性干细胞进行晶状体再生。
Nature. 2016 Mar 17;531(7594):323-8. doi: 10.1038/nature17181. Epub 2016 Mar 9.
3
In vivo cardiac reprogramming contributes to zebrafish heart regeneration.体内心脏重编程有助于斑马鱼心脏再生。
视网膜疾病的光遗传学与靶向基因治疗：解读基本原理、应用及未来展望
J Clin Med. 2024 Jul 19;13(14):4224. doi: 10.3390/jcm13144224.
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Gene therapy for inherited retinal diseases: exploiting new tools in genome editing and nanotechnology.遗传性视网膜疾病的基因治疗：利用基因组编辑和纳米技术中的新工具
Front Ophthalmol (Lausanne). 2023 Sep 19;3:1270561. doi: 10.3389/fopht.2023.1270561. eCollection 2023.
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Gene Ther. 2024 May;31(5-6):199-201. doi: 10.1038/s41434-024-00448-y. Epub 2024 Mar 22.
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