Grishaber J E, McClain K L, Mahoney D H, Fernbach D J
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
Am J Hematol. 1988 Aug;28(4):273-5. doi: 10.1002/ajh.2830280412.
Severe aplastic anemia has been reported in children following Epstein-Barr virus (EBV) infection. The pathophysiology of disease is not known, but an immunologic mechanism is suspected because of the rapid response to steroids. A patient with severe aplastic anemia following EBV infection experienced bone marrow recovery after treatment with high-dose prednisone. After reviewing the literature it is concluded that steroid therapy is indicated in this select group of patients.
据报道，儿童感染爱泼斯坦-巴尔病毒（EBV）后会出现严重再生障碍性贫血。该病的病理生理学尚不清楚，但由于对类固醇治疗反应迅速，怀疑存在免疫机制。一名EBV感染后出现严重再生障碍性贫血的患者在接受大剂量泼尼松治疗后骨髓恢复。查阅文献后得出结论，类固醇疗法适用于这一特定患者群体。
