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全球肾脏健康护理状况评估。

Assessment of Global Kidney Health Care Status.

作者信息

Bello Aminu K, Levin Adeera, Tonelli Marcello, Okpechi Ikechi G, Feehally John, Harris David, Jindal Kailash, Salako Babatunde L, Rateb Ahmed, Osman Mohamed A, Qarni Bilal, Saad Syed, Lunney Meaghan, Wiebe Natasha, Ye Feng, Johnson David W

机构信息

Department of Medicine, University of Alberta, Edmonton, Canada.

Division of Nephrology, University of British Columbia, Vancouver, Canada.

出版信息

JAMA. 2017 May 9;317(18):1864-1881. doi: 10.1001/jama.2017.4046.

Abstract

IMPORTANCE

Kidney disease is a substantial worldwide clinical and public health problem, but information about available care is limited.

OBJECTIVE

To collect information on the current state of readiness, capacity, and competence for the delivery of kidney care across countries and regions of the world.

DESIGN, SETTING, AND PARTICIPANTS: Questionnaire survey administered from May to September 2016 by the International Society of Nephrology (ISN) to 130 ISN-affiliated countries with sampling of key stakeholders (national nephrology society leadership, policy makers, and patient organization representatives) identified by the country and regional nephrology leadership through the ISN.

MAIN OUTCOMES AND MEASURES

Core areas of country capacity and response for kidney care.

RESULTS

Responses were received from 125 of 130 countries (96%), including 289 of 337 individuals (85.8%, with a median of 2 respondents [interquartile range, 1-3]), representing an estimated 93% (6.8 billion) of the world's population of 7.3 billion. There was wide variation in country readiness, capacity, and response in terms of service delivery, financing, workforce, information systems, and leadership and governance. Overall, 119 (95%), 95 (76%), and 94 (75%) countries had facilities for hemodialysis, peritoneal dialysis, and kidney transplantation, respectively. In contrast, 33 (94%), 16 (45%), and 12 (34%) countries in Africa had facilities for hemodialysis, peritoneal dialysis, and kidney transplantation, respectively. For chronic kidney disease (CKD) monitoring in primary care, serum creatinine with estimated glomerular filtration rate and proteinuria measurements were reported as always available in only 21 (18%) and 9 (8%) countries, respectively. Hemodialysis, peritoneal dialysis, and transplantation services were funded publicly and free at the point of care delivery in 50 (42%), 48 (51%), and 46 (49%) countries, respectively. The number of nephrologists was variable and was low (<10 per million population) in Africa, the Middle East, South Asia, and Oceania and South East Asia (OSEA) regions. Health information system (renal registry) availability was limited, particularly for acute kidney injury (8 countries [7%]) and nondialysis CKD (9 countries [8%]). International acute kidney injury and CKD guidelines were reportedly accessible in 52 (45%) and 62 (52%) countries, respectively. There was relatively low capacity for clinical studies in developing nations.

CONCLUSIONS AND RELEVANCE

This survey demonstrated significant interregional and intraregional variability in the current capacity for kidney care across the world, including important gaps in services and workforce. Assuming the responses accurately reflect the status of kidney care in the respondent countries, the findings may be useful to inform efforts to improve the quality of kidney care worldwide.

摘要

重要性

肾病是一个全球性的重大临床和公共卫生问题,但关于现有医疗服务的信息有限。

目的

收集世界各国和各地区在提供肾脏护理方面的准备情况、能力和资质的当前状态信息。

设计、背景和参与者:2016年5月至9月,国际肾脏病学会(ISN)对130个与ISN相关的国家进行问卷调查,通过各国和地区肾脏病学领导层经ISN确定关键利益相关者(国家肾脏病学会领导层、政策制定者和患者组织代表)进行抽样。

主要结果和指标

国家肾脏护理能力和应对措施的核心领域。

结果

130个国家中的125个(96%)回复了问卷,包括337名个人中的289名(85.8%,中位数为2名受访者[四分位间距,1 - 3]),代表了世界73亿人口中约93%(68亿)。各国在服务提供、融资、劳动力、信息系统以及领导和治理方面的准备情况、能力和应对措施差异很大。总体而言,分别有119个(95%)、95个(76%)和94个(75%)国家设有血液透析、腹膜透析和肾脏移植设施。相比之下,非洲分别有33个(94%)、16个(45%)和12个(34%)国家设有血液透析、腹膜透析和肾脏移植设施。对于基层医疗中的慢性肾脏病(CKD)监测,仅分别有21个(18%)和9个(8%)国家报告始终可进行血清肌酐及估算肾小球滤过率和蛋白尿测量。血液透析服务、腹膜透析服务和移植服务在50个(42%)、48个(51%)和46个(49%)国家分别由公共资金资助且在医疗服务点免费提供。肾病科医生数量各不相同,在非洲、中东、南亚、大洋洲和东南亚(OSEA)地区数量较少(每百万人口<10名)。卫生信息系统(肾脏登记处)的可用性有限,特别是对于急性肾损伤(8个国家[7%])和非透析CKD(9个国家[8%])。据报告,分别有52个(45%)和62个(52%)国家可获取国际急性肾损伤和CKD指南。发展中国家的临床研究能力相对较低。

结论及意义

本次调查表明,全球目前在肾脏护理能力方面存在显著的区域间和区域内差异,包括服务和劳动力方面的重要差距。假设这些回复准确反映了受访国家的肾脏护理状况,这些发现可能有助于为提高全球肾脏护理质量的努力提供参考。

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