Vassalotti Joseph A, Francis Anna, Dos Santos Augusto Cesar Soares, Correa-Rotter Ricardo, Abdellatif Dina, Hsiao Li-Li, Roumeliotis Stefanos, Haris Agnes, Kumaraswami Latha A, Lui Siu-Fai, Balducci Alessandro, Liakopoulos Vassilios
Department of Medicine-Renal Medicine, Mount Sinai Hospital, New York, NY, USA.
National Kidney Foundation, Inc., New York, NY, USA.
Clin Exp Nephrol. 2025 Jul 24. doi: 10.1007/s10157-025-02683-y.
Early identification of kidney disease can protect kidney health, prevent kidney disease progression and related complications, reduce cardiovascular disease risk, and decrease mortality. We must ask "Are your kidneys ok?" using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. Evaluation for causes and risk factors for chronic kidney disease (CKD) includes testing for diabetes and measurement of blood pressure and body mass index. This World Kidney Day we assert that case finding in high-risk populations, or even population-level screening, can decrease the burden of kidney disease globally. Early stage CKD is asymptomatic, simple to test for and recent paradigm-shifting CKD treatments such as sodium glucose co-transporter-2 inhibitors dramatically improve outcomes and favor the cost-benefit analysis for screening or case-finding programs. Despite this, numerous barriers exist, including resource allocation, healthcare funding, healthcare infrastructure, and healthcare professional and population awareness of kidney disease. Coordinated efforts by major kidney non-governmental organizations to prioritize the kidney health agenda for governments and aligning early detection efforts with other current programs will maximize efficiencies.
早期识别肾脏疾病可以保护肾脏健康，预防肾脏疾病进展及相关并发症，降低心血管疾病风险，并减少死亡率。我们必须通过血清肌酐来评估肾功能、尿白蛋白来评估肾脏和内皮损伤，询问“你的肾脏还好吗？”。对慢性肾脏病（CKD）病因和危险因素的评估包括糖尿病检测、血压测量和体重指数测量。在今年的世界肾脏日，我们断言，在高危人群中进行病例发现，甚至进行人群层面的筛查，可以减轻全球肾脏疾病负担。早期CKD没有症状，检测简单，而且近期如钠-葡萄糖协同转运蛋白-2抑制剂等改变CKD治疗模式的疗法能显著改善治疗效果，并有利于筛查或病例发现项目的成本效益分析。尽管如此，仍存在许多障碍，包括资源分配、医疗保健资金、医疗保健基础设施，以及医疗保健专业人员和公众对肾脏疾病的认识。主要肾脏非政府组织做出协调努力，为各国政府确定肾脏健康议程的优先事项，并使早期检测工作与其他现有项目保持一致，将实现效率最大化。
