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[慢性情绪性疼痛应激及给大鼠腹腔注射二甲基亚砜时血清中的超氧化物清除活性与转铁蛋白-铜蓝蛋白抗氧化系统]

[Superoxide elimination activity and the transferrin-ceruloplasmin antioxidant system in the blood serum in chronic emotional-pain stress and the administration of dimethyl sulfoxide in rats].

作者信息

Guliaeva N V, Levshina I P, Obidin A B, Avalian A Kh, Kozlov A V

出版信息

Biull Eksp Biol Med. 1988 Aug;106(8):159-60.

PMID:2843247
Abstract

The influence of emotional painful stress (EPS) and dimethyl sulfoxide (DMSO) treatment on ceruloplasmin-transferrin (Cp-Tr) antioxidant system and superoxide dismutase-like activity (SODLA) of the rat serum was studied. No changes in Cp-Tr and SODLA were observed in EPS. On the contrary, DMSO treatment was followed by a decrease in Cp-Tr activity and an increase in SODLA. It is suggested that Cp-Tr and SODLA systems are two interacting antioxidant systems of the serum.

摘要

研究了情绪性疼痛应激(EPS)和二甲基亚砜(DMSO)处理对大鼠血清铜蓝蛋白 - 转铁蛋白(Cp - Tr)抗氧化系统及超氧化物歧化酶样活性(SODLA)的影响。在EPS组中未观察到Cp - Tr和SODLA的变化。相反,DMSO处理后Cp - Tr活性降低,SODLA升高。提示Cp - Tr和SODLA系统是血清中两个相互作用的抗氧化系统。

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