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基因组编辑动物:从转基因作物中吸取教训?

Genome edited animals: Learning from GM crops?

作者信息

Bruce Ann

机构信息

Science, Technology and Innovation Studies, The University of Edinburgh, Old Surgeons' Hall, High School Yards, Edinburgh, UK.

出版信息

Transgenic Res. 2017 Jun;26(3):385-398. doi: 10.1007/s11248-017-0017-2. Epub 2017 Apr 21.

Abstract

Genome editing of livestock is poised to become commercial reality, yet questions remain as to appropriate regulation, potential impact on the industry sector and public acceptability of products. This paper looks at how genome editing of livestock has attempted to learn some of the lessons from commercialisation of GM crops, and takes a systemic approach to explore some of the complexity and ambiguity in incorporating genome edited animals in a food production system. Current applications of genome editing are considered, viewed from the perspective of past technological applications. The question of what is genome editing, and can it be considered natural is examined. The implications of regulation on development of different sectors of livestock production systems are studied, with a particular focus on the veterinary sector. From an EU perspective, regulation of genome edited animals, although not necessarily the same as for GM crops, is advocated from a number of different perspectives. This paper aims to open up new avenues of research on genome edited animals, extending from the current primary focus on science and regulation, to engage with a wider-range of food system actors.

摘要

家畜的基因组编辑有望成为商业现实,但在适当监管、对行业部门的潜在影响以及产品的公众可接受性方面仍存在问题。本文探讨了家畜基因组编辑如何试图从转基因作物商业化中吸取一些经验教训,并采用系统方法来探索将基因编辑动物纳入食品生产系统中的一些复杂性和模糊性。从过去技术应用的角度审视了基因组编辑的当前应用。研究了什么是基因组编辑以及它是否可被视为自然的问题。研究了监管对家畜生产系统不同部门发展的影响,特别关注兽医部门。从欧盟的角度来看,从多个不同角度倡导对基因编辑动物进行监管,尽管不一定与转基因作物的监管相同。本文旨在开辟关于基因编辑动物的新研究途径,从目前对科学和监管的主要关注扩展到与更广泛的食品系统参与者互动。

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本文引用的文献

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