Gab-Alla Amr A
Ophthalmology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Clin Ophthalmol. 2017 Apr 4;11:613-618. doi: 10.2147/OPTH.S133200. eCollection 2017.
To determine the incidence of interface fluid syndrome (IFS) secondary to steroid-induced elevation of intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) in myopic Egyptian patients.
This retrospective case series study was conducted at El-Gowhara Private Eye Center. The medical records of 1,807 patients (3,489 eyes), who underwent LASIK to correct myopia from April 2012 to December 2015 were included. The patients were operated on and reviewed by one surgeon (AAG) for IFS after LASIK associated with elevation of IOP (as compared to preoperative values).
This paper reports the incidence of 2.9% (54 patients) (102 eyes) of IFS induced by increased IOP after LASIK in Egyptian patients. The medical records of 1,807 patients (3,489 eyes) with mean age ± standard deviation (SD) 26.4±2.7 years, who presented with mean myopia ± SD -4.50±1.3 D, mean astigmatism ± SD -1.43±0.8, mean IOP ± SD 15.2±1.2 mmHg, and mean central corneal thickness ± SD 549±25.6 μm, were included. The preoperative anterior and posterior segments, corneal topography, and Schirmer's test were unremarkable.
Limiting topical steroids and routinely measuring the IOP post-LASIK are necessary steps to prevent IFS, especially in case of myopia. A high index of suspicion is required to make a diagnosis. High-resolution optical coherence tomography is helpful to confirm the diagnosis.
确定埃及近视患者在准分子原位角膜磨镶术(LASIK)后因类固醇诱导的眼压(IOP)升高继发的界面液体积聚综合征(IFS)的发生率。
本回顾性病例系列研究在El-Gowhara私立眼科中心进行。纳入了2012年4月至2015年12月期间接受LASIK矫正近视的1807例患者(3489只眼)的病历。患者接受了一名外科医生(AAG)的手术,并在LASIK后因IOP升高(与术前值相比)接受了IFS检查。
本文报道了埃及患者LASIK后因IOP升高诱发的IFS发生率为2.9%(54例患者)(102只眼)。纳入了1807例患者(3489只眼)的病历,其平均年龄±标准差(SD)为26.4±2.7岁,平均近视度数±SD为-4.50±1.3 D,平均散光度数±SD为-1.43±0.8,平均IOP±SD为15.2±1.2 mmHg,平均中央角膜厚度±SD为549±25.6μm。术前眼前节和后节、角膜地形图和泪液分泌试验均无异常。
限制局部使用类固醇并常规测量LASIK术后的IOP是预防IFS的必要措施,尤其是在近视患者中。诊断需要高度怀疑指数。高分辨率光学相干断层扫描有助于确诊。