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头颈部淋巴瘤——十年回顾性观察

Head and neck lymphomas - a retrospective ten-year observation.

作者信息

Niemiec Marcelina, Stryjewska-Makuch Grażyna, Janik Małgorzata, Kolebacz Bogdan, Lisowska Grażyna, Ścierski Wojciech

机构信息

Department of Laryngology and Laryngological Oncology, Silesian Medical University in Katowice, Poland.

Department of Biomedical Computer System, Institute of Informatics, University of Silesia, Katowice, Poland.

出版信息

Contemp Oncol (Pozn). 2017;21(1):66-69. doi: 10.5114/wo.2017.66659. Epub 2017 Mar 22.

DOI:10.5114/wo.2017.66659
PMID:28435401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5385481/
Abstract

AIM OF THE STUDY

Lymphomas are a heterogeneous group of tumours of lymphoid tissue in which there is an abnormal proliferation of cells of the lymphatic system. The literature notes a gradual increase in the incidence of this type of cancer in the whole population. The aim of the study was to evaluate whether the above tendency occurs in the head and neck area.

MATERIAL AND METHODS

In the years 2005-2014, at the Otolaryngology and Laryngological Oncology Department of the Upper Silesian Medical Centre in Katowice, 77 cases of lymphoma were recorded, 58 of which were analysed in terms of location, histological type, age and sex of the patient, and the presence of risk factors.

RESULTS

The vast majority of them were non-Hodgkin's lymphomas (NHL) - 67.53%. Hodgkin's lymphomas (HL) accounted for only a small fraction of diagnoses (7.79%). In terms of histopathological types, in most cases of NHL, there occurred diffuse large B-cell lymphomas (DLBCL) - 51.92%. The most common location was the lymph nodes, representing the location of the primary lesion in more than half of the cases. As regards the extranodal location, the Waldeyer ring dominated (54.54%) along with the palatal tonsil (40.90%). There has been a significant upward trend, especially in the incidence of NHL.

摘要

研究目的

淋巴瘤是淋巴组织肿瘤的异质性群体,其中淋巴系统细胞异常增殖。文献指出,这类癌症在整个人口中的发病率呈逐渐上升趋势。本研究的目的是评估上述趋势在头颈部区域是否存在。

材料与方法

2005年至2014年期间,在卡托维兹上西里西亚医学中心的耳鼻喉科和喉肿瘤学部门,记录了77例淋巴瘤病例,其中58例根据患者的病变部位、组织学类型、年龄和性别以及危险因素的存在情况进行了分析。

结果

其中绝大多数是非霍奇金淋巴瘤(NHL)——67.53%。霍奇金淋巴瘤(HL)仅占诊断病例的一小部分(7.79%)。就组织病理学类型而言,在大多数NHL病例中,出现的是弥漫性大B细胞淋巴瘤(DLBCL)——51.92%。最常见的病变部位是淋巴结,超过半数病例的原发病变位于此处。至于结外病变部位,瓦尔代尔环占主导地位(54.54%),腭扁桃体次之(40.90%)。出现了显著的上升趋势,尤其是NHL的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e6/5385481/a6e654b3b8ca/WO-21-29664-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e6/5385481/a6e654b3b8ca/WO-21-29664-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84e6/5385481/a6e654b3b8ca/WO-21-29664-g001.jpg

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