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关节镜清创术与自体条件血浆治疗骨关节炎的疗效

Outcome of Treatment of Osteoarthritis with Arthroscopic Debridement and Autologous Conditioned Plasma.

作者信息

King Ckk, Yung A

机构信息

Department of Orthopaedics, Changi General Hospital, Singapore.

出版信息

Malays Orthop J. 2017 Mar;11(1):23-27. doi: 10.5704/MOJ.1703.008.

Abstract

INTRODUCTION

Worldwide estimates are that 9.6% of men and 18.0% of women aged over 60 years have symptomatic osteoarthritis. The current treatment options vary from conservative to joint replacement. Recently, debridement of the joint has become an option for symptomatic relief. We evaluated the outcome of arthroscopic debridement with autologous conditioned plasma. The latter helps to promote cellular repair. We have evaluated our results over a two year period.

MATERIALS AND METHODS

We retrospectively analyzed a cohort of 52 patients who underwent arthroscopic knee debridement with autologous conditioned plasma in 2011. The patients were followed up in clinic till discharge. The case notes were reviewed and baseline demographic data obtained. This included age, medical history, occupation, range of movement, BMI measurements, duration of operation and radiographic scores. We analyzed the outcomes against those factors.

RESULTS

Of the 52 patients in our study, 16 were female and 36 were male. The mean follow-up period in the clinic was 6.5 months. The Kellgren-Lawrence score was 21.2% Grade 1, 13.5% Grade 2, 51.9% Grade 3 and 13.5% Grade 4. Improvement in range of movement was seen in 32.7% of patients.

CONCLUSIONS

This study shows that arthroscopic debridement with autologous conditioned plasma (ACP) has a role to play in the treatment of osteoarthritis. In view of these findings, we recommend that surgeons should consider arthroscopic debridement with autologous conditioned plasma as part of their treatment armamentarium.

摘要

引言

据全球估计,60岁以上的男性中有9.6%、女性中有18.0%患有症状性骨关节炎。目前的治疗选择从保守治疗到关节置换不等。最近,关节清创术已成为缓解症状的一种选择。我们评估了自体浓缩血浆关节镜清创术的效果。后者有助于促进细胞修复。我们在两年时间内评估了我们的结果。

材料与方法

我们回顾性分析了2011年接受自体浓缩血浆关节镜膝关节清创术的52例患者。患者在门诊随访至出院。查阅病历并获取基线人口统计学数据。这包括年龄、病史、职业、活动范围、体重指数测量值、手术持续时间和影像学评分。我们针对这些因素分析了结果。

结果

在我们研究的52例患者中,16例为女性,36例为男性。门诊平均随访期为6.5个月。凯尔格伦-劳伦斯评分为1级的占21.2%,2级的占13.5%,3级的占51.9%,4级的占13.5%。32.7%的患者活动范围有所改善。

结论

本研究表明,自体浓缩血浆(ACP)关节镜清创术在骨关节炎治疗中具有一定作用。鉴于这些发现,我们建议外科医生应考虑将自体浓缩血浆关节镜清创术作为其治疗手段的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2796/5393110/48045bf51422/moj-11-023-f1.jpg

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