伊朗肝移植受者代谢综合征的患病率。
Prevalence of Metabolic Syndrome in Liver Transplant Recipients in Iran.
作者信息
Masoumi S J, Mazloom Z, Rezaianzadeh A, Nikeghbalian S, Malek-Hosseini S A, Salahi H
机构信息
School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Nutrition and Food Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Int J Organ Transplant Med. 2016;7(2):85-90. Epub 2016 May 1.
BACKGROUND
Metabolic syndrome (MetSx) is common among liver transplant recipients. It contributes to morbidity and mortality.
OBJECTIVE
To determine the prevalence of MetSx in patients undergoing liver transplantation (LTx) in Iran.
METHODS
202 liver transplant recipients of both sexes completed this study. Relevant information including age, sex, the underlying disease, systolic and diastolic blood pressure, waist circumference, fasting serum levels of blood sugar (FBS), triglyceride (TG), and HDL-cholesterol were measured. The prevalence of MetSx was evaluated at 1, 3, 6, 9, and 12 months after LTx.
RESULTS
The prevalence of MetSx was 36.6% after 1 month that decreased to 28.2% after 12 months of follow-up. The lowest prevalence of MetSx (27.7%) was observed 9 months after LTx. Our data showed a decrease in TG and an increase in HDL-C level and no significant changes in blood pressure, waist circumference and FBS during the study period.
CONCLUSION
The prevalence of MetSx after LTx is high when compared to the normal population. It seems that a change in diet after transplantation may affect the prevalence of MetSx.
背景
代谢综合征（MetSx）在肝移植受者中很常见。它会导致发病和死亡。
目的
确定伊朗肝移植（LTx）患者中MetSx的患病率。
方法
202名男女肝移植受者完成了本研究。测量了包括年龄、性别、基础疾病、收缩压和舒张压、腰围、空腹血糖（FBS）、甘油三酯（TG）和高密度脂蛋白胆固醇在内的相关信息。在肝移植后1、3、6、9和12个月评估MetSx的患病率。
结果
1个月后MetSx的患病率为36.6%，随访12个月后降至28.2%。肝移植后9个月观察到MetSx的患病率最低（27.7%）。我们的数据显示，在研究期间TG降低，HDL-C水平升高，血压、腰围和FBS无显著变化。
结论
与正常人群相比，肝移植后MetSx的患病率较高。移植后饮食的改变似乎可能影响MetSx的患病率。
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