Department of Gastroenterology and Hepatology, Mayo Clinic and Foundation, MN, USA.
J Hepatol. 2010 Jul;53(1):199-206. doi: 10.1016/j.jhep.2010.01.040. Epub 2010 Mar 31.
Metabolic syndrome is common among liver transplant recipients before and after transplantation. The components of metabolic syndrome are often exacerbated in the post-transplant period by transplant specific factors, such as immunosuppression, and are strong predictors of patient morbidity and mortality. Many aspects of the metabolic syndrome are modifiable. Early recognition, prevention and treatment of post-transplant hypertension, obesity, dyslipidemia and diabetes may impact long-term post-transplant survival. Further study into the prevention and management of these issues in the transplant patient are needed.
代谢综合征在肝移植受者移植前后均很常见。移植后，代谢综合征的成分常因移植特异性因素（如免疫抑制）而加重，是患者发病率和死亡率的强有力预测因素。代谢综合征的许多方面是可以改变的。早期识别、预防和治疗移植后高血压、肥胖、血脂异常和糖尿病可能会影响移植后的长期生存。需要进一步研究如何预防和管理移植患者的这些问题。
