Gholami Kheirollah, Laali Elaheh, Abolhassani Hassan, Ahmadvand Alireza, Mohebbi Niayesh, Javadi Mohammad Reza, Aghamohammadi Asghar, Rezaei Nima
Dept. of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Public Health. 2017 Mar;46(3):342-350.
Primary immunodeficiency diseases (PID) are heterogeneous group of inherited disorders mainly characterized by recurrent infections leading to several times hospital admissions. The economic impact of PID is a challenging issue; therefore, this study was designed to determine the medical costs of hospitalizations in this group of patients as an indicator of the direct cost of these diseases.
One hundred and ten children with PID hospitalized in the Children's Medical Center Hospital, Tehran, Iran were included in this study during Jan 2011 and Jan 2012. All direct costs during the admission period were calculated, using the hospital information system.
Medical cost was 7.090$ per patient per admission. Among them, about 1.580$ belong to drug consuming during hospitalization. Anti-infective drugs for systemic use were the most cost-consuming group of drugs, followed by alimentary tract and metabolism and blood and blood forming organs agents. Investigation of anti-infective group internally showed that immune sera and immunoglobulin and antiviral agents for systemic use consisting the most important medication for PID patients during hospital admission.
Although the results of economic evaluations in a region cannot necessarily be applied to other regions, having an overall estimation of hospital admission costs and types of drugs used during admission could be helpful in health policy system.
原发性免疫缺陷病(PID)是一组遗传性疾病,具有异质性,主要特征为反复感染,导致多次住院。PID的经济影响是一个具有挑战性的问题;因此,本研究旨在确定该组患者的住院医疗费用,作为这些疾病直接成本的一个指标。
2011年1月至2012年1月期间,纳入了在伊朗德黑兰儿童医学中心医院住院的110例PID患儿。利用医院信息系统计算住院期间的所有直接成本。
每位患者每次住院的医疗费用为7090美元。其中,约1580美元属于住院期间的药品费用。全身用抗感染药物是最昂贵的药品类别,其次是消化道及代谢和血液及造血器官用药。对抗感染药物组内部的调查显示,免疫血清和免疫球蛋白以及全身用抗病毒药物是PID患者住院期间最重要的用药。
虽然一个地区的经济评估结果不一定能应用于其他地区,但对住院费用及住院期间所用药物类型进行总体评估可能有助于卫生政策体系。