Gülşen Uğur, Şentürk Mehmet Fatih
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bulent Ecevit University, Zonguldak, Turkey.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Süleyman Demirel University, 32260, Çünür, Isparta, Turkey.
BMC Oral Health. 2017 Apr 24;17(1):79. doi: 10.1186/s12903-017-0371-8.
To evaluate the efficacy of platelet-rich fibrine (PRF) on postoperative edema and pain after impacted mandibular third molar surgery.
The prospective study was comprised 30 patients who presented for the removal of bilateral impacted mandibular third molar teeth. After extraction, the sockets were filled with PRF or without PRF in the study and control groups, respectively. Postoperative edema was measured with a flexible tape measure by calculating the distance between several facial landmarks on postoperative days two and seven. Postoperative pain was evaluated with a line-type visual analogue scale (VAS) and a verbal scale (VRS). SPSS version 20.0 was used for data analysis.
Both groups recorded significant improvement compared to the baseline levels in almost all of the outcome variables. There was no statistically significant difference between the study and control groups (p > 0.05).
Using or not using PRF to reduce postoperative pain and edema in third molar surgery was equally successful.
This study was retrospectively registered at the ISRCTN registry ( ISRCTN16849867 ) on 6 March 2017.
评估富血小板纤维蛋白（PRF）对下颌阻生第三磨牙拔除术后水肿和疼痛的疗效。
本前瞻性研究纳入30例因双侧下颌阻生第三磨牙需拔除的患者。拔牙后，研究组和对照组拔牙窝分别填充PRF或不填充PRF。术后第2天和第7天，通过计算面部几个标志点之间的距离，使用软尺测量术后水肿情况。采用线性视觉模拟量表（VAS）和语言量表（VRS）评估术后疼痛。使用SPSS 20.0版进行数据分析。
与基线水平相比，两组几乎所有结局变量均有显著改善。研究组和对照组之间无统计学显著差异（p＞0.05）。
在第三磨牙手术中，使用或不使用PRF减轻术后疼痛和水肿同样有效。
本研究于2017年3月6日在国际标准随机对照试验编号注册库（ISRCTN16849867）进行回顾性注册。
