Kettering Klaus, Yim Dag-Hau, Albert Caroline, Gramley Felix
Department of Cardiology, University of Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
HPK Heidelberger Praxisklinik für Innere Medizin, Kardiologie und Pneumologie, Heidelberg, Germany.
Herzschrittmacherther Elektrophysiol. 2017 Dec;28(4):403-408. doi: 10.1007/s00399-017-0499-x. Epub 2017 Apr 24.
Catheter ablation has become the first line of therapy in patients with symptomatic, recurrent, drug-refractory atrial fibrillation. However, catheter ablation of persistent atrial fibrillation is still a challenge. Various relatively complex ablation strategies exist and their results are not very favorable. Therefore, the aim of our study was to evaluate a well-defined reasonable approach to catheter ablation of persistent atrial fibrillation. The strategy consisted of a circumferential pulmonary vein ablation in combination with a linear lesion at the roof of the left atrium.
A total of 150 patients with symptomatic persistent atrial fibrillation were enrolled in this study. All patients underwent catheter ablation of persistent atrial fibrillation using the abovementioned approach.
The ablation procedure could be performed as planned in all 150 patients. Five years after catheter ablation, the success rate was 71.3% (no arrhythmia recurrence in 107 out of 150 patients). There were no major complications during long-term follow-up.
Catheter ablation of persistent atrial fibrillation can be performed safely and effectively using this ablation strategy providing favorable long-term follow-up results.
导管消融已成为有症状、复发性、药物难治性心房颤动患者的一线治疗方法。然而,持续性心房颤动的导管消融仍然是一项挑战。存在各种相对复杂的消融策略,但其结果并不十分理想。因此,我们研究的目的是评估一种明确合理的持续性心房颤动导管消融方法。该策略包括环肺静脉消融联合左心房顶部线性消融。
本研究共纳入150例有症状的持续性心房颤动患者。所有患者均采用上述方法进行持续性心房颤动的导管消融。
150例患者均按计划完成消融手术。导管消融术后5年,成功率为71.3%(150例患者中有107例无心律失常复发)。长期随访期间无重大并发症发生。
采用这种消融策略进行持续性心房颤动的导管消融可安全有效地进行,并能提供良好的长期随访结果。