Tchernev Georgi, Lozev Ilia, Pidakev Ivan, Mangarov Hristo, Grigorov Yavor, Cardoso José Carlos, Popchristova Elisaveta, Patterson James W, Lotti Torello, Pehlivanov Georgi, Voicu Cristiana, Clatici Victor Gabriel, Wollina Uwe
Department of Dermatology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR), General Skobelev 79, 1606, Sofia, Bulgaria.
Venereology and Dermatologic Surgery, Onkoderma - Policlinic for Dermatology, 26 General Skobelev blvd, Sofia, Bulgaria.
Wien Med Wochenschr. 2018 Nov;168(15-16):423-426. doi: 10.1007/s10354-017-0558-2. Epub 2017 Apr 24.
Interdigital melanoma, as a subtype of acral lentiginous melanoma, is relatively uncommon in the Caucasian population. It frequently goes unrecognized for a prolonged period of time prior to diagnosis, due to its asymptomatic nature and variable clinical appearance.
We report the case of a 67-year-old Caucasian woman who presented with interdigital malignant melanoma affecting two neighboring interdigital spaces. It had evolved over a period of more than 15 years and had been initially misdiagnosed as tinea pedis due to the macerated appearance of the lesion and a positive mycologic examination.
We highlight the striking involvement of two adjacent interdigital spaces and the neighboring area of the sole of the foot by the tumor. The melanoma was staged as IIIC, with pathologic grading T4bN2bM CONCLUSIONS: The involvement of two adjacent interdigital spaces is unusual and, to our knowledge, has not been previously highlighted in the medical literature. It may be explained, in part, by the longstanding nature of the lesion in our patient.
指间黑色素瘤作为肢端雀斑样痣黑色素瘤的一种亚型，在白种人群中相对少见。由于其无症状的性质和多变的临床表现，在诊断前常被长时间漏诊。
我们报告了一例67岁的白种女性病例，该患者患有指间恶性黑色素瘤，累及两个相邻的指间间隙。其病程超过15年，最初因病变浸渍外观和真菌学检查阳性而被误诊为足癣。
我们强调了肿瘤对两个相邻指间间隙及足底相邻区域的显著累及。该黑色素瘤分期为IIIC期，病理分级为T4bN2bM0。
累及两个相邻指间间隙的情况并不常见，据我们所知，此前医学文献中尚未对此进行过重点描述。这可能部分归因于我们患者病变的长期存在。
